ArticleAmerican journal of preventive medicine2021
The Dose-Response Relationship Between Physical Activity and Cardiometabolic Health in Adolescents.
Article in American journal of preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Non-linear effect of physical activity intervention on blood pressure in children and adolescents: a systematic review and dose-response meta-analysis.BMC public health · 2025Pooled it
- School-based physical activity programs for promoting physical activity and fitness in children and adolescents aged 6 to 18.The Cochrane database of systematic reviews · 2021Pooled it
- Joint association of physical activity and dietary quality with advanced cardiovascular-kidney-metabolic syndrome in older adults: A population-based study.Atencion primaria · 2026Article
- 24-Hour Movement Behavior and Health-Related Physical Fitness in College Students: A Compositional Data Analysis.International journal of behavioral medicine · 2026Article
- Associations of Screen Time and Physical Activity With Body Mass Index in Early Adolescence: A Prospective Cohort Study.Obesity (Silver Spring, Md.) · 2026Article
- Independent and joint associations of out-of-school time moderate-to-vigorous physical activity and sedentary behavior with the risk of central obesity in children and adolescents.Archives of public health = Archives belges de sante publique · 2026Article
- Association between physical exercise based on FITT principle and vision health among primary school students in Suzhou, China.Frontiers in public health · 2026Article
- No or low self-reported moderate to vigorous physical activity among Chinese children and adolescents: a large-scale cross-sectional study.BMC public health · 2025Article
- Cross-sectional association of fitness, fatness, and dyslipidemia with metabolic syndrome in youth.World journal of clinical pediatrics · 2025Article
- Policy dosing in school physical education and adolescent fitness: a threshold-type association in a two-wave panel study from Kunming, China.Frontiers in public health · 2025Article
- Article
- Energy Costs of 37 Physical Activities in Chinese Children and Adolescents Aged 9-17 Years with Obesity.Nutrients · 2024Article
- Global prevalence and gender inequalities in at least 60 min of self-reported moderate-to-vigorous physical activity 1 or more days per week: An analysis with 707,616 adolescents.Journal of sport and health science · 2024Article
- The association between leisure-time physical activity and blood pressure changes from adolescence to young adulthood: Tehran Lipid and Glucose Study.Scientific reports · 2023Article
- Physical Inactivity and the Role of Bullying Among Gender Minority Youth Participating in the 2017 and 2019 Youth Risk Behavior Survey.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2023Article
- Dose-response relationship between physical activity and cardiometabolic risk in obese children and adolescents: A pre-post quasi-experimental study.Frontiers in physiology · 2023Article
- Integration of Time-Based Recommendations with Current Pediatric Health Behavior Guidelines: Implications for Obesity Prevention and Treatment in Youth.Current obesity reports · 2022Review
- Summary and application of the WHO 2020 physical activity guidelines for patients with essential hypertension in primary care.Heliyon · 2022Review
- Relationship of leisure-time and household physical activity level and type with cardiovascular disease: secondary analysis of the Takashima Study data.BMC cardiovascular disorders · 2022Article
- Effects of Movement Behaviors on Overall Health and Appetite Control: Current Evidence and Perspectives in Children and Adolescents.Current obesity reports · 2022Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
introductionThis study examines the dose-response relationship between moderate-to-vigorous physical activity and cardiometabolic measures in adolescents.
methodsCross-sectional spline analyses were performed using 2003-2016 National Health and Nutrition Examination Survey data among adolescents (aged 12-19 years, N=9,195) on objectively measured (2003-2006) and self-reported (2007-2016) weekly mean minutes of moderate-to-vigorous physical activity and cardiometabolic measures (systolic and diastolic blood pressure, total cholesterol, high-density lipoprotein, BMI, and cardiorespiratory fitness). Inflection points were determined for nonlinear relationships.
resultsFor objective moderate-to-vigorous physical activity, female adolescents had significant nonlinear associations with inflection points at 90 minutes/week for BMI percentile and systolic blood pressure. Male adolescents had inflection points at 150 weekly minutes of objective activity for BMI percentile and cardiorespiratory fitness. BMI percentile was about 7% lower for female and male adolescents at 150 weekly minutes of objectively measured moderate-to-vigorous physical activity than at 0 minutes. For self-reported moderate-to-vigorous physical activity, inflection points were at 375 minutes/week (diastolic blood pressure for female adolescents) and 500 minutes/week (systolic blood pressure for male adolescents).
conclusionsAmong several significant dose-response relationships between physical activity and cardiometabolic health in adolescents, consistent and often nonlinear relationships were identified for BMI, with inflection points at 90-150 minutes of objective moderate-to-vigorous physical activity. Notable differences in associations and linearity were identified by sex and physical activity measure (objective or self-reported). These results support calls for any increase in physical activity among adolescents and suggest that recommendations closer to the adult guidelines of 150 weekly minutes of physical activity may be health promoting and more attainable for youth than the current recommendation of 420 weekly minutes.
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