Evidence map›Paper›PMID 33340671›Full record

ArticleNeurobiology of learning and memory2021

Age- and sex-specific fear conditioning deficits in mice lacking Pcdh10, an Autism Associated Gene.

Sarah L Ferri, Holly C Dow, Hannah Schoch, Ji Youn Lee, Edward S Brodkin, Ted Abel

Open access · greenAbstract read
In one paragraph

Article in Neurobiology of learning and memory, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  5. Anti-angiogenic mechanisms and serotonergic dysfunction in the Rgs2 knockout model for the study of psycho-obstetric risk.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  6. The role of Pcdh10 in neurological disease and cancer.Journal of cancer research and clinical oncology · 2023
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sarah L FerriIowa Neuroscience Institute, Department of Neuroscience and Pharmacology, University of Iowa, 169 Newton Road, 2312 Pappajohn Biomedical Discovery Building, Iowa City, IA 52242, USA.
Holly C DowDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Translational Research Laboratory, 125 South 31(st) Street, Room 2202, Philadelphia, PA 19104-3403, USA.
Hannah SchochDepartment of Biomedical Sciences, Elson S. Floyd College of Medicine, Washington State University, 412 E. Spokane Falls Blvd., Spokane, WA, 99202, USA.
Ji Youn LeeIowa Neuroscience Institute, Department of Neuroscience and Pharmacology, University of Iowa, 169 Newton Road, 2312 Pappajohn Biomedical Discovery Building, Iowa City, IA 52242, USA.
Edward S BrodkinDepartment of Psychiatry, Perelman School of Medicine at the University of Pennsylvania, Translational Research Laboratory, 125 South 31(st) Street, Room 2202, Philadelphia, PA 19104-3403, USA.
Ted AbelIowa Neuroscience Institute, Department of Neuroscience and Pharmacology, University of Iowa, 169 Newton Road, 2312 Pappajohn Biomedical Discovery Building, Iowa City, IA 52242, USA. Electronic address: ted-abel@uiowa.edu.
University of Iowa · USWashington State University Spokane · US

Funding

NMDA Receptor Hypofunction in the Amygdala of Schizophrenia PatientsP50MH096891 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI HAHN, CHANG-GYU · 2012 to 2016
$10.6M
Neurobiology of sociability in a mouse model system relevant to autismR01MH080718 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BRODKIN, EDWARD S · 2007 to 2011
$1.9M
Mechanisms of male-specific amygdala-dependent deficits in approach and avoidance behaviorsK01MH119540 · NIMH · UNIVERSITY OF IOWA · PI FERRI, SARAH L · 2020 to 2023
$551k
NIMH NIH HHS K01 MH119540NIMH NIH HHS P50 MH096891NIMH NIH HHS R01 MH080718
6 · The paper itself

Abstract

PCDH10 is a gene associated with Autism Spectrum Disorder. It is involved in the growth of thalamocortical projections and dendritic spine elimination. Previously, we characterized Pcdh10 haploinsufficient mice (Pcdh10

Indexed as

Age FactorsAnimalsAutism Spectrum DisorderBasolateral Nuclear ComplexCadherinsConditioning, ClassicalDendritic SpinesFearFemaleMaleMiceMice, KnockoutProtocadherinsReceptors, N-Methyl-D-AspartateSex FactorsCadherinsPcdh10 protein, mouseProtocadherinsReceptors, N-Methyl-D-AspartateASDAutismFear conditioningProtocadherinSex differences

Identifiers

PMID33340671
PMCPMC7880893
OpenAlexW3110722071

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.