SynthesisJornal de pediatria
Impact of chronic kidney disease on health-related quality of life in the pediatric population: meta-analysis.
Synthesis in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Beyond Kidney Function: A Neuro-Renal Perspective on Personalized Care in Pediatric Chronic Kidney Disease.Medical sciences (Basel, Switzerland) · 2026Review
- Health-Related Quality of Life in Pediatric Hepatic Glycogen Storage Disease: A Dual-Perspective Study.Nutrients · 2026Article
- Sociodemographic, health, and oral factors associated with health-related quality of life in children and adolescents with chronic kidney disease: a cross-sectional study.BMC public health · 2026Observational
- Trajectories of health-related quality of life in youth with chronic physical illness and their siblings.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Pediatric advanced chronic kidney disease as a family challenge: coping and communication in daily life.European journal of pediatrics · 2026Article
- Pediatric Chronic Kidney Disease: Mind the Gap Between Reality and Expectations.Children (Basel, Switzerland) · 2025Review
- Machine learning approaches for predicting and diagnosing chronic kidney disease: current trends, challenges, solutions, and future directions.International urology and nephrology · 2025Review
- Cost-Effectiveness of Intensive Blood Pressure Control in Youth With Chronic Kidney Disease.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Common mental health conditions and considerations in pediatric chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2024Review
- Comparisons of EQ-5D-Y and PedsQL in pediatric patients with mild-to-moderate chronic kidney disease in longitudinal analyses.Health and quality of life outcomes · 2023Article
- Patient-Reported Outcomes Over 24 Months in Pediatric CKD: Findings From the MyKidneyHealth Cohort Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023Article
- Symptoms for early diagnosis of chronic kidney disease in children - a machine learning-based score.European journal of pediatrics · 2023Article
- Cross-Cultural Validation of Health and Quality of Life Measures for Children in Hong Kong.Occupational therapy international · 2022Article
- Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study.International journal of pediatrics · 2021Article
- Quality of Life and Associated Factors among Mothers with Gestational Diabetes Mellitus by using a Specific GDMQ-36 Questionnaire: A Cross-Sectional Study.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo meta-analyze health-related quality of life in pediatric patients with chronic kidney disease in comparison to healthy patients according to the dimensions of the PedsQL instrument. SOURCES OF DATA: A systematic review was performed with meta-analysis for the mean difference in each of the health-related quality of life dimensions. The authors searched for ten scientific databases including PubMed, Scopus, SciELO, Science Direct, ProQuest, Google Scholar. Reproducibility by the Kappa index was evaluated, and Dersimonian and Laird's tests, RI coefficient, Begg statistic, Forest Plot, and sensitivity analysis were carried out. SUMMARY OF THE
findings17 investigations were included in the qualitative synthesis and 7 in the quantitative synthesis with a population of 1214 of both healthy and sick pediatric patients with 3-5 chronic kidney disease stages. The health-related quality of life in pediatric chronic kidney disease patients presented lower scores in all the evaluated dimensions: in the physical dimension the difference is of 13.6 points, in the emotional dimension 7.8, in the social dimension 8.2, in the school dimension 20.8, with the total difference being 17.7 points.
conclusionThe findings of this study show that pediatric patients have lower health-related quality of life in all the evaluated dimensions, with the "school" dimension being the most affected and the "emotional" one the least. In this sense, we suggest monitoring the health-related quality of life of pediatric patients with chronic kidney disease so that interventions can be oriented to strengthen the affected dimensions, including adjustments to daily life and prevention of complications related to the disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.