ReviewPhysiological reports2021
Cortisol level dysregulation and its prevalence-Is it nature's alarm clock?
Review in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.
- Impact of menopause hormone therapy, exercise, and their combination on bone mineral density and mental wellbeing in menopausal women: a scoping review.Frontiers in reproductive health · 2025Pooled it
- Article
- Effects of High-Intensity Interval Training on Steroid Hormones and Psychological Outcomes in Healthy Male Adolescents: A Randomized Controlled Trial.Sports (Basel, Switzerland) · 2026Article
- Fear of cancer recurrence and change in hair cortisol concentrations in partners of breast cancer survivors.Journal of cancer survivorship : research and practice · 2026Article
- Longitudinal assessment of changes in hair cortisol levels and associations with violence, poor mental health and harmful substance use among female sex workers in Nairobi, Kenya.PLOS global public health · 2026Article
- Nutritional Quality Fingerprinting of Wild and FarmedBiology · 2025Article
- Regulation of therapeutic protein release in response to circadian biomarkers.Nature communications · 2025Article
- Biomarkers as diagnostic or prognostic indicators of delirium: examining the current evidence.British journal of neuroscience nursing · 2025Article
- Mindfulness Improves Awareness and Cortisol Levels During COVID-19 Lockdown: A Randomised Controlled Trial in Healthcare Workers.Healthcare (Basel, Switzerland) · 2025Article
- Cortisol Detection Methods and the Hormone's Role in Evaluating Circadian Rhythm Disruption.International journal of molecular sciences · 2025Review
- Effects of Weight-Cutting Practices on Sleep, Recovery, and Injury in Combat Sports: A Scoping Review.Journal of functional morphology and kinesiology · 2025Review
- Treating musculoskeletal conditions with a bit of exercise and manual therapy: are you kidding me? It's time for us to evolve again.The Journal of manual & manipulative therapy · 2025Article
- Sensory processing sensitivity in adult dental patients and its relation to perceived stress, cortisol, and serotonin secretion.Scientific reports · 2025Article
- Prevalence and influencing factors of occupational burnout among healthcare workers in the Chinese mainland during the late 2022 Omicron COVID-19 outbreak: a multicenter cross-sectional study.BMC public health · 2025Article
- Prevalence and associated factors of post-traumatic stress disorder among women with an experience of intimate partner violence (IPV): Insights from urban slums of Bangladesh.Global mental health (Cambridge, England) · 2025Article
- Weight stigma and mental health symptoms: mediation by perceived stress.Frontiers in psychiatry · 2025Article
- Association between metabolic score for insulin resistance and lower limb pain among the elderly: a cross-sectional study.Frontiers in endocrinology · 2025Article
- The Impact of Psychological Stress on Wound Healing: Implications for Neocollagenesis and Scar Treatment Efficacy.Clinical, cosmetic and investigational dermatology · 2025Review
- Predictors of Inflammation-Mediated Preterm Birth.Physiology (Bethesda, Md.) · 2025Review
- Serum Cortisol and Cardiovascular Disease Risk - A Potential Biomarker.Current cardiology reviews · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
This review examines the stress hormone cortisol which plays an important role in regulating and supporting different bodily functions. Disruption in cortisol production has an impact on health and this review looks at a wide range of papers where cortisol has been indicated as a factor in numerous chronic conditions-especially those which are classed as "noncommunicable diseases" (NCDs). Timely detection, screening, and treatment for NCDs are vital to address the growing problem of NCDs worldwide-this would have health and socioeconomic benefits. Interestingly, many of the papers highlight the pro-inflammatory consequences of cortisol dysregulation and its deleterious effects on the body. This is particularly relevant given the recent findings concerning COVID-19 where pro-inflammatory cytokines have been implicated in severe inflammation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.