Evidence map›Paper›PMID 33340255›Full record

ArticlePM & R : the journal of injury, function, and rehabilitation2021

Menstrual Irregularity, Hormonal Contraceptive Use, and Bone Stress Injuries in Collegiate Female Athletes in the United States.

Jennifer Cheng, Kristen A Santiago, Zafir Abutalib, Kate E Temme, Ann Hulme, Marci A Goolsby, Carrie L Esopenko, Ellen K Casey

Open access · greenAbstract read
In one paragraph

Article in PM & R : the journal of injury, function, and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Approach to sport-savvy contraceptive counselling for athletes.Canadian family physician Medecin de famille canadien · 2026
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  11. Editorial: Women in sports 2022.Frontiers in physiology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jennifer ChengDepartment of Physiatry, Hospital for Special Surgery, New York, NY, USA.ORCID 0000-0001-8458-619X
Kristen A SantiagoDepartment of Physiatry, Hospital for Special Surgery, New York, NY, USA.ORCID 0000-0002-5813-2669
Zafir AbutalibBiostatistics Core, Hospital for Special Surgery, New York, NY, USA.
Kate E TemmeDepartment of Physical Medicine and Rehabilitation, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Ann HulmeDepartment of Physical Medicine and Rehabilitation, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Marci A GoolsbyDepartment of Primary Care Sports Medicine, Hospital for Special Surgery, New York, NY, USA.
Carrie L EsopenkoDepartment of Rehabilitation and Movement Sciences, Rutgers Biomedical Health Sciences, Newark, NJ, USA.
Ellen K CaseyDepartment of Physiatry, Hospital for Special Surgery, New York, NY, USA.ORCID 0000-0003-0139-8826
Hospital for Special Surgery · USHospital of the University of Pennsylvania · USRutgers, The State University of New Jersey · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
NCATS NIH HHS UL1 TR002384
6 · The paper itself

Abstract

backgroundMenstrual irregularity (MI) is common in female athletes and is a component of the Female Athlete Triad (Triad). Many athletes with the Triad are started on hormonal contraceptives (HC) for MI, but this interferes with the ability to monitor menstrual cycle regularity and can mask other causes of MI. There are limited studies investigating the relationship between MI, HC use, and injury in female collegiate athletes.

objectiveTo examine the prevalence of and relationship between HC use, MI, and bone stress injuries in female collegiate athletes in the United States.

designCross-sectional study.

settingOnline survey.

participants1020 U.S. female collegiate athletes (age ≥ 18 years). METHODS OR

interventionsAssessment of risk factors for menstrual irregularity and bone stress injuries was conducted via a one-time survey.

main outcome measuresHC use, MI, history of stress fractures.

resultsCurrent HC use prevalence was 65% (95% confidence interval [CI], 61.9%, 67.8%). Of all athletes, 47% reported past MI. Of the athletes who were not currently using HCs, 32% had current MI. Compared with athletes without past MI, more athletes with past MI reported current HC use (73% vs. 57%) and indicated menstrual cycle consistency as the primary reason for use (24% vs. 4%) (P < .001). Additionally, 25% of athletes reported a history of stress fractures, which was associated with lean/aesthetic sports participation (odds ratio [95% CI]: 1.9 [1.4, 2.5]; P < .001) and less oral contraceptive pill (OCP) use (0.7 [0.5, 1.0]; P = .043). Compared with OCPs, injectable HCs were associated with greater odds of a history of stress fractures (4.5[1.6, 12.3]; P = .004).

conclusionsHC use was prevalent among this cohort of female collegiate athletes, and almost half of the athletes reported past MI. A goal of menstrual cycle regularity was cited by 24% of athletes as a primary reason to use HCs, which shows that more athlete education is needed to avoid masking MI and the Triad with HCs. Further studies elucidating the relationship between HC use, MI, and sports-related injury are warranted.

Indexed as

Athletic InjuriesFemale Athlete Triad SyndromeAdolescentAthletesContraceptive AgentsCross-Sectional StudiesFemaleHumansMenstruation DisturbancesUnited StatesContraceptive Agents

Identifiers

PMID33340255
PMCPMC8262270
OpenAlexW3117880494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.