ArticleMedicina oral, patologia oral y cirugia bucal2021
Cervical lymph node metastasis in squamous cell carcinoma of the buccal mucosa: a retrospective study on pattern of involvement and clinical analysis.
Article in Medicina oral, patologia oral y cirugia bucal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Prediction model for occult lymph node metastasis of head and neck squamous cell carcinoma based on multi-dimensional indicators.American journal of translational research · 2026Article
- Multimodal imaging of cervical lymphadenopathy: diagnostic value and clinical applications.Medicine and pharmacy reports · 2025Review
- Prognostic Implications of T Cell Receptor Repertoire Diversity in Cervical Lymph Nodes of Oral Squamous Cell Carcinoma Patients.International journal of molecular sciences · 2025Article
- The clinical target volume delineation based on the correlation analysis of neck node levels in oral cavity squamous cell carcinoma (OCSCC).BMC cancer · 2024Article
- The role of unconventional lymph node metastasis in neck recurrence among patients with tongue cancer.Clinical oral investigations · 2023Article
- A preoperative nomogram model for the prediction of lymph node metastasis in buccal mucosa cancer.Cancer medicine · 2023Article
- Buccinator muscle invasion is a risk factor for cervical lymph node metastasis in squamous cell carcinoma of the buccal mucosa: A retrospective study.Oncology letters · 2023Article
- Protection of the marginal mandibular branches of the facial nerves by different surgical procedures in comprehensive cervical lymphadenectomy for locally advanced oral and oropharyngeal cancer: a multicenter experience.World journal of surgical oncology · 2023Article
- Cyclin D1 and Ki-67 expression and its correlation with histopathological parameters and cervical lymph node metastasis in oral squamous cell carcinoma.Dental research journal · 2023Article
- Clinicopathological Characteristics and Survival Outcomes of Patients with Buccal Squamous Cell Carcinoma: Results of a Multi-Institutional Study.Medicina (Kaunas, Lithuania) · 2021Article
- A New Approach for Diagnosing Oral Epithelial Dysplasia: A Proposal for a Novel Histopathological Scoring System.Journal of microscopy and ultrastructureArticle
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6 authors.
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Abstract
backgroundThe study was performed with an aim to map the pattern of metastasis of squamous cell carcinomas of buccal mucosa to various cervical lymph node levels and analyze its correlation with primary tumor size and histo-pathological grading. MATERIAL AND
methods254 patients with squamous cell carcinoma of the buccal mucosa treated with surgery first approach were analyzed retrospectively. The tumor size was noted from pre-operative CT Scans and were divided into early and advanced tumors. The resected specimen was studied to note the histo-pathological grading of the squamous cell carcinoma and the metastatic deposits at various lymph node levels.
resultsOut of 254 patients (149 females, 105 males), 145 patients showed histo-pathologically proven metastatic deposits in one or more lymph nodes out of which there were 56 patients showing occult metastasis. 78/145 patients showed metastatic involvement of level IB and/or IA lymph nodes, 31 showed involvement of level II and/or I lymph nodes, 27 showed involvement of level III with or without involvement of level I and II and 9 showed metastasis to level IV and V lymph nodes with or without level I, II or III lymph nodes. Cervical lymph node metastasis had statistically significant association with tumor size with advanced tumors showing worse pattern of metastatic spread beyond level I and II lymph nodes. As the degree of differentiation of squamous cell carcinoma reduced, they were more prone for cervical metastasis with moderately and poorly differentiated squamous cell carcinoma showing higher involvement of level III, IV and V lymph nodes.
conclusionsThe majority of buccal mucosa cases showed metastasis to level I, II and III lymph nodes out of which level IB and/or IA was most frequently involved. Metastasis to level IV and V lymph nodes was rare and was seen especially in patients with advanced primary tumor and poor histo-pathologic differentiation.
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