SynthesisMedicina oral, patologia oral y cirugia bucal2021
Retrograde filling material in periapical surgery: a systematic review.
Synthesis in Medicina oral, patologia oral y cirugia bucal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- The outcome of combined use of iRoot BP Plus and iRoot SP for root-end filling in endodontic microsurgery: a randomized controlled trial.Clinical oral investigations · 2024Trial
- Assessment of guided versus non-guided endodontic microsurgery with root-end resection using different retrograde filling materials on operation time and lesion volume: A randomized controlled clinical study.Journal of conservative dentistry and endodontics · 2026Article
- Microshear Bond Strength of Composite Resin to Mineral Trioxide Aggregate and Potassium Nitrate-Modified Polycarboxylate Cement at Two Time Points Using Different Adhesive Approaches: An In Vitro Study.Clinical and experimental dental research · 2026Article
- Bibliometric Analysis of the Worldwide Scientific Production on Periapical Lesions in Veterinary Medicine: Visualization, Emerging Patterns, and Thematic Evolution.Veterinary medicine international · 2026Article
- Marginal Adaptability of Harvard MTA and Biodentine Used as Root-End Filling Material: A Comparative SEM Study.Materials (Basel, Switzerland) · 2025Article
- Endodontic Re-Surgery With Simultaneous Recession Coverage Using a Modified Flap Design After Failed Primary Apicoectomy: A Case Report.Clinical case reports · 2025Article
- Evaluation of Void Volume and Blood Contamination-Induced Changes in Surface Microhardness of Calcium Silicate-Based Cement, Sealer, and Their Combination (Lid Technique) in Retrograde Filling.European endodontic journal · 2025Article
- Endodontic bioceramics: current and futurity aspects.Frontiers in oral health · 2025Review
- Article
- Platelet-Rich Fibrin: A Self-Derived Biomaterial for Surgical Treatment of a Periapical Lesion.Cureus · 2024Article
- Antibacterial Activity and Sustained Effectiveness of Calcium Silicate-Based Cement as a Root-End Filling Material againstMaterials (Basel, Switzerland) · 2023Article
- The Washout Resistance of Bioactive Root-End Filling Materials.Materials (Basel, Switzerland) · 2023Article
- Biological properties of Ceraputty as a retrograde filling material: an in vitro study on hPDLSCs.Clinical oral investigations · 2023Article
- Bioceramics in Endodontics: Updates and Future Perspectives.Bioengineering (Basel, Switzerland) · 2023Review
- Effectiveness of different root-end filling materials in modern surgical endodontic treatment: A systematic review and network meta-analysis.Journal of dental sciences · 2022Article
- MTA as modulator of periapical tissue healing in rat molar: A histological study.Journal of oral biology and craniofacial researchArticle
Corrections and comments
- Commented on by
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriapical surgery focuses on the treatment of teeth with persistent periapical lesions when orthograde root canal treatment fails. Although MTA® is the gold standard material for retrograde filling, Biodentine® - a tricalcium silicate-based cement - has been proposed in order to resolve several of its limitations. A systematic review has been carried out to compare the physicochemical properties of Biodentine® versus MTA® as root-end filling material in periapical surgery. MATERIAL AND
methodsAn electronic search was conducted by two independent examiners during March 2020 in the Cochrane, PubMed-MEDLINE and Scopus databases. In addition, a manual search was made in specialized journals. Comparative human or in vitro studies that evaluated bond strength, the presence of marginal gap and sealing ability were included. No restriction on publication date was applied. Animal studies, clinical cases, cases series and expert opinions were excluded.
resultsAfter analyzing 147 initially selected studies, 13 publications were included. Regarding bond strength, the studies seemed to evidence better performance of Biodentine® in both acidic and blood contaminated environments. In relation to the presence of marginal gap and sealing ability, the studies yielded contradictory results. According to some authors, the sealing ability of Biodentine® is greater than that of MTA® during the first 24 hours, though both materials prove equal after one week. Other authors recorded no significant differences.
conclusionsConsidering the limitations and heterogeneity of the studies included, there is not sufficient evidence to confirm the clinical superiority of Biodentine® as a root-end filling material in periapical surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.