Evidence map›Paper›PMID 33340054›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Evaluation of [

Sanni Tuominen, Thomas Keller, Nataliia Petruk, Francisco López-Picón, Dominik Eichin, Eliisa Löyttyniemi, Alejandra Verhassel, Johan Rajander, Jouko Sandholm, Johanna Tuomela and 1 more

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. TSPO Radioligands for Neuroinflammation: An Overview.Molecules (Basel, Switzerland) · 2024
    Review
  4. Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  5. Article
  6. Evaluation of [Molecular imaging and biology · 2022
    Article
  7. Imaging translocator protein expression with positron emission tomography.European journal of nuclear medicine and molecular imaging · 2021
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sanni TuominenPreclinical Imaging Laboratory, Turku PET Centre, University of Turku, Tykistökatu 6A, FI-20520, Turku, Finland.
Thomas KellerRadiopharmaceutical Chemistry Laboratory, Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland.
Nataliia PetrukInstitute of Biomedicine and FICAN West Cancer Research Laboratory, University of Turku, Kiinamyllynkatu 10, FI-20520, Turku, Finland.
Francisco López-PicónPreclinical Imaging Laboratory, Turku PET Centre, University of Turku, Tykistökatu 6A, FI-20520, Turku, Finland.
Dominik EichinMediCity Research Laboratory, University of Turku, Tykistökatu 6A, FI-20520, Turku, Finland.
Eliisa LöyttyniemiDepartment of Biostatistics, University of Turku, Kiinamyllynkatu 10, FI-20520, Turku, Finland.
Alejandra VerhasselInstitute of Biomedicine and FICAN West Cancer Research Laboratory, University of Turku, Kiinamyllynkatu 10, FI-20520, Turku, Finland.
Johan RajanderAccelerator Laboratory, Turku PET Centre, Åbo Akademi University, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland.
Jouko SandholmTurku Bioscience Centre, University of Turku and Åbo Akademi University, Tykistökatu 6A, FI-20520, Turku, Finland.
Johanna TuomelaInstitute of Biomedicine and FICAN West Cancer Research Laboratory, University of Turku, Kiinamyllynkatu 10, FI-20520, Turku, Finland.
Tove J GrönroosPreclinical Imaging Laboratory, Turku PET Centre, University of Turku, Tykistökatu 6A, FI-20520, Turku, Finland. tovgro@utu.fi.ORCID http://orcid.org/0000-0003-4468-0805
University of Turku · FIÅbo Akademi University · FI

Funding

Finnish Governmental Research Funding for Turku University Hospital 13142Svenska Kulturfonden 139742Turku University Foundation 260982
6 · The paper itself

Abstract

backgroundMany malignant tumours have increased TSPO expression, which has been related to a poor prognosis. TSPO-PET tracers have not comprehensively been evaluated in peripherally located tumours. This study aimed to evaluate whether N,N-diethyl-2-(2-(4-([

methodsRT was used to induce inflammatory responses in HNSCC xenografts and cells. [

resultsIn vivo imaging and ex vivo measurement revealed significantly higher [

conclusions[

Indexed as

Fluorine RadioisotopesHead and Neck NeoplasmsAnimalsPositron-Emission TomographyPyrazolesPyrimidinesTissue DistributionFluorine RadioisotopesPyrazolesPyrimidines[18F]F-DPAHead and neck cancerPETRadiotherapyTSPO

Identifiers

PMID33340054
PMCPMC8113193
OpenAlexW3115100169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.