Evidence map›Paper›PMID 33339950›Full record

ArticleScientific reports2020

Chemical genetic approach using β-rubromycin reveals that a RIO kinase-like protein is involved in morphological development in Phytophthora infestans.

Shuji Tani, Naotaka Nishio, Kenji Kai, Daisuke Hagiwara, Yoshiyuki Ogata, Motoaki Tojo, Jun-Ichi Sumitani, Howard S Judelson, Takashi Kawaguchi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Shuji TaniGraduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, 599-8531, Japan. shuji@biochem.osakafu-u.ac.jp.
Naotaka NishioGraduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, 599-8531, Japan.
Kenji KaiGraduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, 599-8531, Japan.
Daisuke HagiwaraMedical Mycology Research Center, Chiba University, Chiba, Japan.
Yoshiyuki OgataGraduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, 599-8531, Japan.
Motoaki TojoGraduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, 599-8531, Japan.
Jun-Ichi SumitaniGraduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, 599-8531, Japan.
Howard S JudelsonDepartment of Microbiology and Plant Pathology, University of California, Riverside, Riverside, CA, USA.
Takashi KawaguchiGraduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka, 599-8531, Japan.
Osaka Prefecture University · JPChiba University Hospital · JPUniversity of California, Riverside · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To characterize the molecular mechanisms underlying life-stage transitions in Phytophthora infestans, we initiated a chemical genetics approach by screening for a stage-specific inhibitor of morphological development from microbial culture extracts prepared mostly from actinomycetes from soil in Japan. Of the more than 700 extracts, one consistently inhibited Ph. infestans cyst germination. Purification and identification of the active compound by ESI-MS,

Indexed as

Amino Acid SequencePhytophthora infestansPlant DiseasesProtein Serine-Threonine KinasesQuinonesSpores, Fungalbeta-rubromycinProtein Serine-Threonine KinasesQuinones

Identifiers

PMID33339950
PMCPMC7749174
OpenAlexW3114386109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.