ArticleNPJ breast cancer2020
Association between the histopathological growth patterns of liver metastases and survival after hepatic surgery in breast cancer patients.
Article in NPJ breast cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 41 citations in OpenAlex.
- Clinicopathological insights and management of liver metastases: Current advances and future perspectives.World journal of hepatology · 2025Review
- Transcriptomic characterization of the histopathological growth patterns in breast cancer liver metastases.Clinical & experimental metastasis · 2024Article
- Spatial Transcriptome Mapping of the Desmoplastic Growth Pattern of Colorectal Liver Metastases by In Situ Sequencing Reveals a Biologically Relevant Zonation of the Desmoplastic Rim.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024Article
- Histopathological Growth Patterns Determine the Outcomes of Colorectal Cancer Liver Metastasis Following Liver Resection.Cancers · 2024Article
- Histopathological growth patterns and tumor-infiltrating lymphocytes in breast cancer liver metastases.NPJ breast cancer · 2023Article
- An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver.Nature communications · 2023Article
- Histopathological growth patterns of neuroendocrine tumor liver metastases.Clinical & experimental metastasis · 2023Article
- Comment on 'Use the term "infiltrative" instead of "replacement" when defining histopathological growth pattern in patients with liver cancer' by Kong B et al.British journal of cancer · 2023Article
- Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution.Molecular cancer · 2023Article
- Histopathological growth pattern of liver metastases as an independent marker of metastatic behavior in different primary cancers.Frontiers in oncology · 2023Article
- Histopathological Growth Pattern in Colorectal Liver Metastasis and The Tumor Immune Microenvironment.Cancers · 2022Review
- CT, MRI, and radiomics studies of liver metastasis histopathological growth patterns: an up-to-date review.Abdominal radiology (New York) · 2022Review
- Histopathological growth patterns of resected non-colorectal, non-neuroendocrine liver metastases: a retrospective multicenter study.Clinical & experimental metastasis · 2022Article
- Delineating the molecular landscape of different histopathological growth patterns in colorectal cancer liver metastases.Frontiers in immunology · 2022Article
- Runt related transcription factor-1 plays a central role in vessel co-option of colorectal cancer liver metastases.Communications biology · 2021Article
- Claudin-2 promotes colorectal cancer liver metastasis and is a biomarker of the replacement type growth pattern.Communications biology · 2021Article
- Clinico-metabolic characterization improves the prognostic value of histological growth patterns in patients undergoing surgery for colorectal liver metastases.Journal of surgical oncology · 2021Article
- Different Forms of Tumor Vascularization and Their Clinical Implications Focusing on Vessel Co-option in Colorectal Cancer Liver Metastases.Frontiers in cell and developmental biology · 2021Review
- Association between the histopathological growth patterns of liver metastases and survival after hepatic surgery in breast cancer patients.NPJ breast cancer · 2020Article
Corrections and comments
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Authors and funding
21 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Currently, there are no markers to identify patients with liver-only or liver-dominant metastases that would benefit from hepatic surgery. Here we characterized histopathological growth patterns (HGPs) of liver metastases in a consecutive series of 36 breast cancer patients who underwent hepatic surgery. Survival analyses showed that the presence of a desmoplastic HGP in the liver metastases (a rim of fibrous tissue separating cancer cells from the liver parenchyma, present in 20 (56%) patients) is independently associated with favorable progression-free and overall survival when compared with the replacement HGP (cancer cells growing into the liver parenchyma, present in 16 (44%) patients).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.