Evidence map›Paper›PMID 33339758›Full record

Trial reportBrazilian journal of otorhinolaryngology

Vestibular rehabilitation therapy in combination with transcranial direct current stimulation (tDCS) for treatment of chronic vestibular dysfunction in the elderly: a double-blind randomized controlled trial.

Nader Saki, Arash Bayat, Soheila Nikakhlagh, Golshan Mirmomeni

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Brazilian journal of otorhinolaryngology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. The Effectiveness of Vestibular Rehabilitation in Vestibular Migraine: A Systematic Review.Journal of the Association for Research in Otolaryngology : JARO · 2026
    Pooled it
  2. Evaluation of effective methods in the treatment of residual dizziness after BPPV: a randomized comparative clinical study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nader SakiAhvaz Jundishapur University of Medical Sciences, Hearing Research Center, Ahvaz, Iran.
Arash BayatAhvaz Jundishapur University of Medical Sciences, Hearing Research Center, Ahvaz, Iran; Ahvaz Jundishapur University of Medical Sciences, School of Rehabilitation Sciences, Musculoskeletal Rehabilitation Center, Ahvaz, Iran. Electronic address: arashbayat2004@yahoo.com.
Soheila NikakhlaghAhvaz Jundishapur University of Medical Sciences, Hearing Research Center, Ahvaz, Iran.
Golshan MirmomeniAhvaz Jundishapur University of Medical Sciences, Students Research Committee, Ahvaz, Iran.
Ahvaz Jundishapur University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDizziness and imbalance are common dysfunctions in the elderly. Vestibular rehabilitation therapy is an effective method to alleviate chronic dizziness in patients with vestibular dysfunction. Transcranial direct current stimulation has reportedly improved balance function in patients with vestibular dysfunction.

objectiveThis study was conducted to investigate the therapeutic efficacy of vestibular rehabilitation combined with transcranial direct current stimulation in elderly patients with vestibular dysfunction.

methodsIn a double-blinded randomized controlled trial, 36 elderly patients with chronic vestibular dysfunction were randomly assigned to either vestibular rehabilitation and transcranial direct current stimulation (n = 18) or vestibular rehabilitation alone (n = 18) group. The transcranial stimulation protocol consisted of multisession bifrontal electrical stimulation of the dorsolateral prefrontal cortex (2 mA intensity and 20 min duration), followed by rehabilitation exercises. The vestibular rehabilitation protocol consisted of habituation and adaptation exercises combined with gait exercises during a three week period. The primary outcome of this study was the dizziness handicap inventory score, and the secondary outcomes were activities-specific balance confidence and Beck anxiety inventory scores.

resultsFor the dizziness handicap score, the repeated-measures analysis of variance showed a significant main effect of "time", "stimulation" and stimulation × time interaction effect. There was a significant reduction in the overall dizziness handicap score with "time" for both the groups, which was more pronounced in the vestibular rehabilitation and electrical stimulation group. In terms of activities-specific balance confidence change scores, we found a significant main effect of "time" and "stimulation" main factors, but this effect for stimulation × time interaction was not significant. For the Beck anxiety score, we observed a significant main effect of "time", but no evidence for the main effect of the "stimulation" factor.

conclusionBifrontal transcranial direct current stimulation in combination with vestibular rehabilitation therapy is a promising approach to improve chronic vestibular symptoms in the elderly.

Indexed as

Transcranial Direct Current StimulationVestibule, LabyrinthAgedDizzinessDouble-Blind MethodExercise TherapyHumansTreatment OutcomeVertigoAnxietyBalanceElderlyTranscranial direct current stimulationVestibular rehabilitation

Identifiers

PMID33339758
PMCPMC9483938
OpenAlexW3108368068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.