Evidence map›Paper›PMID 33339466›Full record

SynthesisPalliative medicine2021

Effectiveness and implementation of palliative care interventions for patients with chronic obstructive pulmonary disease: A systematic review.

Johanna Mc Broese, Albert H de Heij, Daisy Ja Janssen, Julia A Skora, Huib Am Kerstjens, Niels H Chavannes, Yvonne Engels, Rianne Mjj van der Kleij

Abstract readSystematic Review
In one paragraph

Synthesis in Palliative medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Cough and dyspnea management in pulmonary fibrosis.Current opinion in supportive and palliative care · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Social determinants of advanced chronic respiratory interventions: a scoping review.European respiratory review : an official journal of the European Respiratory Society · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Johanna Mc BroesePublic Health & Primary care, Leiden University Medical Centre, Leiden, The Netherlands.ORCID 0000-0003-4815-2305
Albert H de HeijCentre of Expertise for Palliative Care, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.ORCID 0000-0002-8085-3358
Daisy Ja JanssenDepartment of Research & Development, CIRO, Horn, The Netherlands.ORCID 0000-0002-1827-9869
Julia A SkoraPublic Health & Primary care, Leiden University Medical Centre, Leiden, The Netherlands.
Huib Am Kerstjensdepartment of Respiratory Medicine & Tuberculosis, and Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands.
Niels H ChavannesPublic Health & Primary care, Leiden University Medical Centre, Leiden, The Netherlands.
Yvonne EngelsAnaesthesiology, Pain & Palliative Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID 0000-0002-7669-1018
Rianne Mjj van der KleijPublic Health & Primary care, Leiden University Medical Centre, Leiden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough guidelines recommend palliative care for patients with chronic obstructive pulmonary disease, there is little evidence for the effectiveness of palliative care interventions for this patient group specifically.

aimTo describe the characteristics of palliative care interventions for patients with COPD and their informal caregivers and review the available evidence on effectiveness and implementation outcomes.

designSystematic review and narrative synthesis (PROSPERO CRD42017079962). DATA SOURCES: Seven databases were searched for articles reporting on multi-component palliative care interventions for study populations containing ⩾30% patients with COPD. Quantitative as well as qualitative and mixed-method studies were included. Intervention characteristics, effect outcomes, implementation outcomes and barriers and facilitators for successful implementation were extracted and synthesized qualitatively.

resultsThirty-one articles reporting on twenty unique interventions were included. Only four interventions (20%) were evaluated in an adequately powered controlled trial. Most interventions comprised of longitudinal palliative care, including care coordination and comprehensive needs assessments. Results on effectiveness were mixed and inconclusive. The feasibility level varied and was context-dependent. Acceptability of the interventions was high; having someone to call for support and education about breathlessness were most valued characteristics. Most frequently named barriers were uncertainty about the timing of referral due to the unpredictable disease trajectory (referrers), time availability (providers) and accessibility (patients).

conclusionLittle high-quality evidence is yet available on the effectiveness and implementation of palliative care interventions for patients with COPD. There is a need for well-conducted effectiveness studies and adequate process evaluations using standardized methodologies to create higher-level evidence and inform successful implementation.

Indexed as

Hospice and Palliative Care NursingPulmonary Disease, Chronic ObstructiveCaregiversDyspneaHumansPalliative CarebreathlessnessChronic obstructive pulmonary diseasepalliative carequality of lifesystematic review

Identifiers

PMID33339466
PMCPMC7975862

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.