Evidence map›Paper›PMID 33339425›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Effect of Rosmarinic Acid and Ionizing Radiation on Glutathione in Melanoma B16F10 Cells: A Translational Opportunity.

Amparo Olivares, Miguel Alcaraz-Saura, Daniel Gyingiri Achel, Miguel Alcaraz

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Amparo OlivaresRadiology and Physical Medicine Department, School of Medicine, University of Murcia, 30100 Espinardo, Murcia, Spain.
Miguel Alcaraz-SauraRadiology and Physical Medicine Department, School of Medicine, University of Murcia, 30100 Espinardo, Murcia, Spain.
Daniel Gyingiri AchelApplied Radiation Biology Centre, Radiological and Medical Sciences Research Institute, Ghana Atomic Energy Commission, Legon-Accra GE-257-0465, Ghana.
Miguel AlcarazRadiology and Physical Medicine Department, School of Medicine, University of Murcia, 30100 Espinardo, Murcia, Spain.
Universidad de Murcia · ESGhana Atomic Energy Commission · GH

Funding

National Spanish R&D Programme CENIT of the Spanish Ministry of Science and Technology. Industrial Research and Experimental Development of Intelligent Foods (Acronym: SMARTFOODS).
6 · The paper itself

Abstract

To explain a paradoxical radiosensitizing effect of rosmarinic acid (RA) on the melanoma B16F10 cells, we analyzed the glutathione (GSH) intracellular production on this cell (traditionally considered radioresistant) in comparison with human prostate epithelial cells (PNT2) (considered to be radiosensitive). In PNT2 cells, the administration of RA increased the total GSH content during the first 3 h (

Indexed as

B16F10glutathione, melanomaPNT2radiation effectsradiosensitizers

Identifiers

PMID33339425
PMCPMC7767074
OpenAlexW3117226942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.