Evidence map›Paper›PMID 33339359›Full record

Trial reportNutrients2020

Caffeine-Containing Energy Shots Cause Acute Impaired Glucoregulation in Adolescents.

Jane Shearer, Raylene A Reimer, Dustin S Hittel, Mackenzie A Gault, Hans J Vogel, Matthias S Klein

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jane ShearerDepartment of Biochemistry and Molecular Biology, Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0002-1224-979X
Raylene A ReimerDepartment of Biochemistry and Molecular Biology, Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 4N1, Canada.ORCID 0000-0001-5088-7947
Dustin S HittelDepartment of Biochemistry and Molecular Biology, Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 4N1, Canada.
Mackenzie A GaultDepartment of Biochemistry and Molecular Biology, Faculty of Kinesiology, University of Calgary, Calgary, AB T2N 4N1, Canada.
Hans J VogelDepartment of Biological Sciences, Faculty of Science, University of Calgary, Calgary, AB T2N 1N4, Canada.
Matthias S KleinCollege of Food, Agricultural and Environmental Sciences, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0001-7455-5381
University of Calgary · CAThe Ohio State University · US

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN 2018-04238
6 · The paper itself

Abstract

Caffeine-containing, nutritionally fortified energy shots are consumed at high rates by adolescents, yet little is known about their metabolic impact. The purpose of this study was to examine the consequences of small format, caffeinated energy shots on glucose metabolism and gastrointestinal hormone secretion in adolescents. Twenty participants aged 13-19 years participated in a double-blind, randomized cross-over study consisting of two trials separated by 1-4 weeks. Participants consumed a volume-matched caffeinated energy shot (CAF, 5 mg/kg) or a decaffeinated energy shot (DECAF) followed by a 2 h oral glucose tolerance test. Blood samples were collected and area under the curve (AUC) calculated for glucose, insulin and gut and metabolic hormones. Consumption of CAF resulted in a 25% increase in glucose and a 26% increase in insulin area under the curve (AUC,

Indexed as

Energy DrinksAcute DiseaseAdolescentArea Under CurveBlood GlucoseCaffeineCross-Over StudiesDouble-Blind MethodFemaleGastrointestinal HormonesGlucose IntoleranceGlucose Tolerance TestHumansHyperinsulinismInsulinMaleBlood GlucoseCaffeineGastrointestinal HormonesInsulinadolescentadverse reactionenergy drinkmetabolomicspediatrics

Identifiers

PMID33339359
PMCPMC7766305
OpenAlexW3112248594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.