Evidence map›Paper›PMID 33339269›Full record

ArticleHealthcare (Basel, Switzerland)2020

Novel Prefrontal Synthesis Intervention Improves Language in Children with Autism.

Andrey Vyshedskiy, Edward Khokhlovich, Rita Dunn, Alexander Faisman, Jonah Elgart, Lisa Lokshina, Yuriy Gankin, Simone Ostrovsky, Lauren deTorres, Stephen M Edelson and 1 more

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Dietary Factors Impact Developmental Trajectories in Young Autistic Children.Journal of autism and developmental disorders · 2024
    Article
  6. Article
  7. Article
  8. Functionality of Apps for People with Autism: Comparison between Educators from Florence and Granada.International journal of environmental research and public health · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Andrey VyshedskiyBiology Department, Boston University, Boston, MA 02215, USA.ORCID 0000-0002-1610-8716
Edward KhokhlovichIndependent Researcher, Newton, MA 02459, USA.
Rita DunnImagiRation, Boston, MA 02135, USA.
Alexander FaismanIndependent Researcher, New York, NY 10002, USA.
Jonah ElgartImagiRation, Boston, MA 02135, USA.
Lisa LokshinaImagiRation, Boston, MA 02135, USA.
Yuriy GankinQuantori, Cambridge, MA 02139, USA.
Simone OstrovskyImagiRation, Boston, MA 02135, USA.ORCID 0000-0002-4201-4959
Lauren deTorresImagiRation, Boston, MA 02135, USA.
Stephen M EdelsonAutism Research Institute, San Diego, CA 91911, USA.
Petr O IlyinskiiIndependent Researcher, Cambridge, MA 02140, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prefrontal synthesis (PFS) is defined as the ability to juxtapose mental visuospatial objects at will. Paralysis of PFS may be responsible for the lack of comprehension of spatial prepositions, semantically-reversible sentences, and recursive sentences observed in 30 to 40% of individuals with autism spectrum disorder (ASD). In this report we present data from a three-year-long clinical trial of 6454 ASD children age 2 to 12 years, which were administered a PFS-targeting intervention. Tablet-based verbal and nonverbal exercises emphasizing mental-juxtaposition-of-objects were organized into an application called

Indexed as

ASDautismimaginationlanguage delaylanguage therapytheory of mind

Identifiers

PMID33339269
PMCPMC7765988

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.