Evidence map›Paper›PMID 33339195›Full record

ArticleBiomedicines2020

Nancy D Ebelt, Edith Zuniga, Monica Marzagalli, Vic Zamloot, Bruce R Blazar, Ravi Salgia, Edwin R Manuel

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Exploiting bacteria for cancer immunotherapy.Nature reviews. Clinical oncology · 2024
    Review
  7. Hypoxia-targeting bacteria in cancer therapy.Seminars in cancer biology · 2024
    Review
  8. Review
  9. Acta biochimica et biophysica Sinica · 2023
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Acta pharmaceutica Sinica. B · 2021
    Article
  15. Review
  16. Collagenase-ExpressingCancers · 2021
    Article
  17. Integration ofCancers · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nancy D EbeltDepartment of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
Edith ZunigaDepartment of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
Monica MarzagalliDepartment of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
Vic ZamlootDepartment of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
Bruce R BlazarDepartment of Pediatrics, Division of Blood and Bone Marrow Transplantation, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Ravi SalgiaDepartment of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, CA 91010, USA.ORCID 0000-0001-9643-7626
Edwin R ManuelDepartment of Immuno-Oncology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA.
City of Hope · USCity Of Hope National Medical Center · USUniversity of Minnesota Medical Center · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
Trial Design and Biostatistical Support CoreP01CA065493 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Mark J Osborn · 1995 to 2026
$48.2M
Beckman Research Institute, City of Hope Shared Resources GrantNational Comprehensive Cancer Network Young Investigator AwardNCI NIH HHS P01 CA065493NCI NIH HHS P30 CA033572NCI NIH HHS P30CA033572
6 · The paper itself

Abstract

Therapeutic options for non-small cell lung cancer (NSCLC) treatment have changed dramatically in recent years with the advent of novel immunotherapeutic approaches. Among these, immune checkpoint blockade (ICB) using monoclonal antibodies has shown tremendous promise in approximately 20% of patients. In order to better predict patients that will respond to ICB treatment, biomarkers such as tumor-associated CD8

Indexed as

anti-CTLA4anti-PD-1immune checkpoint blockadeindoleamine 2,3-dioxygenasenon-small cell lung cancerSalmonella typhimuriumsmall-hairpin RNA

Identifiers

PMID33339195
PMCPMC7765568
OpenAlexW3110973200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.