Evidence map›Paper›PMID 33339141›Full record

ReviewInternational journal of environmental research and public health2020

Dietary Thiols: A Potential Supporting Strategy against Oxidative Stress in Heart Failure and Muscular Damage during Sports Activity.

Mariarita Brancaccio, Cristina Mennitti, Arturo Cesaro, Fabio Fimiani, Elisabetta Moscarella, Martina Caiazza, Felice Gragnano, Annaluisa Ranieri, Giovanni D'Alicandro, Nadia Tinto and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Cripto Is Targeted by miR-1a-3p in a Mouse Model of Heart Development.International journal of molecular sciences · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Metabolic Treatment of Wolfram Syndrome.International journal of environmental research and public health · 2022
    Review
  11. The Biological Role of Vitamins in Athletes' Muscle, Heart and Microbiota.International journal of environmental research and public health · 2022
    Review
  12. Review
  13. Article
  14. Vascular Ageing and Aerobic Exercise.International journal of environmental research and public health · 2021
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Mariarita BrancaccioDepartment of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Naples, Italy.ORCID 0000-0002-4161-512X
Cristina MennittiDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0001-6355-5976
Arturo CesaroDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Naples, Italy.ORCID 0000-0003-4435-1235
Fabio FimianiInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Monaldi Hospital, 81100 Naples, Italy.
Elisabetta MoscarellaDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Naples, Italy.
Martina CaiazzaInherited and Rare Cardiovascular Diseases, Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Monaldi Hospital, 81100 Naples, Italy.
Felice GragnanoDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Naples, Italy.ORCID 0000-0002-6943-278X
Annaluisa RanieriCeinge Biotecnologie Avanzate S. C. a R. L., 80131 Naples, Italy.
Giovanni D'AlicandroDepartment of Neuroscience and Rehabilitation, Center of Sports Medicine and Disability, AORN, Santobono-Pausillipon, 80122 Naples, Italy.
Nadia TintoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.
Cristina MazzaccaraDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0001-7774-2799
Barbara LombardoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0003-3884-1043
Raffaela PeroDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.
Giuseppe LimongelliDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Naples, Italy.ORCID 0000-0002-8291-9517
Giulia FrissoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.
Paolo CalabròDepartment of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", 81100 Naples, Italy.ORCID 0000-0002-5018-830X
Olga ScudieroDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, 80131 Naples, Italy.ORCID 0000-0002-4916-4976
University of Campania "Luigi Vanvitelli" · ITCeinge Biotecnologie Avanzate (Italy) · ITUniversity of Naples Federico II · ITStazione Zoologica Anton Dohrn · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moderate exercise combined with proper nutrition are considered protective factors against cardiovascular disease and musculoskeletal disorders. However, physical activity is known not only to have positive effects. In fact, the achievement of a good performance requires a very high oxygen consumption, which leads to the formation of oxygen free radicals, responsible for premature cell aging and diseases such as heart failure and muscle injury. In this scenario, a primary role is played by antioxidants, in particular by natural antioxidants that can be taken through the diet. Natural antioxidants are molecules capable of counteracting oxygen free radicals without causing cellular cytotoxicity. In recent years, therefore, research has conducted numerous studies on the identification of natural micronutrients, in order to prevent or mitigate oxidative stress induced by physical activity by helping to support conventional drug therapies against heart failure and muscle damage. The aim of this review is to have an overview of how controlled physical activity and a diet rich in antioxidants can represent a "natural cure" to prevent imbalances caused by free oxygen radicals in diseases such as heart failure and muscle damage. In particular, we will focus on sulfur-containing compounds that have the ability to protect the body from oxidative stress. We will mainly focus on six natural antioxidants: glutathione, taurine, lipoic acid, sulforaphane, garlic and methylsulfonylmethane.

Indexed as

DietHeart FailureSulfhydryl CompoundsAntioxidantsHumansOxidative StressReactive Oxygen SpeciesAntioxidantsReactive Oxygen SpeciesSulfhydryl Compoundsathletesheart failuremuscle damage and diet supplementationoxidative stresssport activitysulfur-containing compounds

Identifiers

PMID33339141
PMCPMC7765667
OpenAlexW3111355345

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.