Evidence map›Paper›PMID 33338976›Full record

ArticleThrombosis research2021

Incidence of symptomatic venous thromboembolism following hospitalization for coronavirus disease 2019: Prospective results from a multi-center study.

Farid Rashidi, Stefano Barco, Farin Kamangar, Gustavo A Heresi, Ashkan Emadi, Cihangir Kaymaz, Pavel Jansa, Abilio Reis, Arash Rashidi, Ali Taghizadieh and 25 more

Open access · bronzeAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Thrombosis research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
1.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 72 citations in OpenAlex.

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  4. Thrombotic and Hemorrhagic Incidences in Patients After Discharge from COVID-19 Infection: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
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  8. A systematic review on post-discharge venous thromboembolism prophylaxis in patients with COVID-19.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 12 institutions in 7 countries.

Farid RashidiTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: fr2652@yahoo.com.
Stefano BarcoCenter for Thrombosis and Hemostasis, Johannes Gutenberg University Mainz, Mainz, Germany; Clinic of Angiology, University Hospital Zurich, Zurich, Switzerland.
Farin KamangarDepartment of Biology, School of Computer, Mathematical, and Natural Sciences, Morgan State University, Baltimore, MD, USA.
Gustavo A HeresiDepartment of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, OH, USA.
Ashkan EmadiDepartment of Medicine, School of Medicine, University of Maryland, Baltimore, USA; Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD, USA.
Cihangir KaymazDepartment of Cardiology, Kosuyolu Heart Education and Research Hospital, University of Health Sciences, 34844 Istanbul, Turkey.
Pavel Jansa2nd Department of Medicine - Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.
Abilio ReisPulmonary Vascular Disease Unit, Medicine Department, Centro Hospitalar Universitário do Porto, Porto, Portugal.
Arash RashidiDivision of Nephrology and Hypertension, University Hospitals Cleveland Medical Center Cleveland, OH, USA.
Ali TaghizadiehTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Parisa RezaeifarTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Minoosh MoghimiDepartment of Hematology & Medical Oncology, Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Samad GhodratiDepartment of Pulmonology, Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Abolfazl MozafariDepartment of Internal Medical, Qom Branch, Islamic Azad University, Qom, Iran.
Ali Alavi FoumaniInflammatory Lung Disease Research Center, Department of Internal Medicine, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Ouria TahamtanTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Effat RafieeDepartment of Pulmonology, Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Zahra AbbaspourDepartment of Endocrinology, Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Kasra KhodadadiDepartment of Internal Medicine, Vali-e-Asr Hospital, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Golsa AlamdariTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Yasman BoodaghiTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Maryam RezaeiTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Muhammad Javad MuhammadiStudent Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
Meysam AbbasiStudent Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.
Fatemeh MovaseghiDepartment of Internal Medical, Qom Branch, Islamic Azad University, Qom, Iran.
Ata KoohiTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Leila ShakourzadTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Fatemeh EbrahimiTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Sarvin RadvarTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Maryam AmoozadehTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Fatemeh FereidooniTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Hanieh NaseariTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Kobra MovalledTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Ozra GhorbaniTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Khalil AnsarinTuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Tabriz University of Medical Sciences · IRZanjan University of Medical Sciences · IRQom Islamic Azad University · IRCentro Hospitalar do Porto · PTCharles University · CZCleveland Clinic · USKartal Koşuyolu High Specialization Training and Research Hospital · TRMorgan State University · USRazi Hospital · IRUniversity Hospital of Zurich · CHUniversity Hospitals of Cleveland · USUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThrombosis and pulmonary embolism appear to be major causes of mortality in hospitalized coronavirus disease 2019 (COVID-19) patients. However, few studies have focused on the incidence of venous thromboembolism (VTE) after hospitalization for COVID-19.

methodsIn this multi-center study, we followed 1529 COVID-19 patients for at least 45 days after hospital discharge, who underwent routine telephone follow-up. In case of signs or symptoms of pulmonary embolism (PE) or deep vein thrombosis (DVT), they were invited for an in-hospital visit with a pulmonologist. The primary outcome was symptomatic VTE within 45 days of hospital discharge.

resultsOf 1529 COVID-19 patients discharged from hospital, a total of 228 (14.9%) reported potential signs or symptoms of PE or DVT and were seen for an in-hospital visit. Of these, 13 and 12 received Doppler ultrasounds or pulmonary CT angiography, respectively, of whom only one patient was diagnosed with symptomatic PE. Of 51 (3.3%) patients who died after discharge, two deaths were attributed to VTE corresponding to a 45-day cumulative rate of symptomatic VTE of 0.2% (95%CI 0.1%-0.6%; n = 3). There was no evidence of acute respiratory distress syndrome (ARDS) in these patients. Other deaths after hospital discharge included myocardial infarction (n = 13), heart failure (n = 9), and stroke (n = 9).

conclusionsWe did not observe a high rate of symptomatic VTE in COVID-19 patients after hospital discharge. Routine extended thromboprophylaxis after hospitalization for COVID-19 may not have a net clinical benefit. Randomized trials may be warranted.

Indexed as

Patient DischargeAdultAgedAged, 80 and overCOVID-19FemaleHumansIncidenceIranMaleMiddle AgedProspective StudiesPulmonary EmbolismRisk FactorsTime FactorsVenous ThromboembolismCohort studyCOVID-19HospitalizationThromboprophylaxisVenous thromboembolism

Identifiers

PMID33338976
PMCPMC7836837
OpenAlexW3111405385

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.