SynthesisOsteoarthritis and cartilage2021
Statistical shape modeling of the hip and the association with hip osteoarthritis: a systematic review.
Synthesis in Osteoarthritis and cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Statistical shape modelling of the human lumbar spine: a scoping review characterising the research landscape and potential clinical applications.Frontiers in bioengineering and biotechnology · 2026Pooled it
- A Systematic Review of the Potential ofInternational journal of molecular sciences · 2025Pooled it
- Severe pincer morphology is associated with incident hip osteoarthritis: prospective individual participant data from 18 935 hips from the World COACH consortium.British journal of sports medicine · 2026Article
- Shape predicts osteoarthritis progression in the first carpometacarpal joint.Frontiers in bioengineering and biotechnology · 2026Article
- Use of dual-energy X-ray absorptiometry to evaluate variation in bone shape and alignment associated with radiographic knee osteoarthritis: Findings from a study of 19,053 individuals in UK Biobank.Osteoarthritis and cartilage open · 2025Article
- Complex Regulatory Interactions at GDF5 Shape Joint Morphology and Osteoarthritis Disease Risk.Arthritis & rheumatology (Hoboken, N.J.) · 2025Article
- Characterizing Shape Variations in Infant Hips Using Statistical Shape Modeling for Ultrasonic Diagnosis of Hip Dysplasia with Graf's Method.Hip & pelvis · 2025Article
- Pain Assessment in Osteoarthritis: Present Practices and Future Prospects Including the Use of Biomarkers and Wearable Technologies, and AI-Driven Personalized Medicine.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Review
- Posture control characteristics of different age groups in China based on BertecFrontiers in neurology · 2025Article
- OpenHands: An Open-Source Statistical Shape Model of the Finger Bones.Annals of biomedical engineering · 2024Article
- Femoroacetabular impingement syndrome in middle-aged individuals is strongly associated with the development of hip osteoarthritis within 10-year follow-up: a prospective cohort study (CHECK).British journal of sports medicine · 2024Article
- Reliability and agreement of manual and automated morphological radiographic hip measurements.Osteoarthritis and cartilage open · 2024Article
- Cartilage Integrity: A Review of Mechanical and Frictional Properties and Repair Approaches in Osteoarthritis.Healthcare (Basel, Switzerland) · 2024Review
- The Association Between the Development of Cam Morphology During Skeletal Growth in High-Impact Athletes and the Presence of Cartilage Loss and Labral Damage in Adulthood: A Prospective Cohort Study With a 12-Year Follow-up.The American journal of sports medicine · 2024Article
- OPTIMIZATION-DRIVEN STATISTICAL MODELS OF ANATOMIES USING RADIAL BASIS FUNCTION SHAPE REPRESENTATION.Proceedings. IEEE International Symposium on Biomedical Imaging · 2024Article
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- Development of Local Software for Automatic Measurement of Geometric Parameters in the Proximal Femur Using a Combination of a Deep Learning Approach and an Active Shape Model on X-ray Images.Journal of imaging informatics in medicine · 2024Article
- Relative Acetabular Retroversion and Its Association With Earlier-Onset Symptomatic Osteoarthritis of the Hip.Arthroplasty today · 2024Article
- Risk Factors and Population-Attributable Fractions for Incident Hip Osteoarthritis.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 11 institutions in 6 countries.
Funding
Abstract
objectiveTo summarize available evidence on the association between hip shape as quantified by statistical shape modeling (SSM) and the incidence or progression of hip osteoarthritis.
designWe conducted a systematic search of five electronic databases, based on a registered protocol (available: PROSPERO CRD42020145411). Articles presenting original data on the longitudinal relationship between radiographic hip shape (quantified by SSM) and hip OA were eligible. Quantitative meta-analysis was precluded because of the use of different SSM models across studies. We used the Newcastle-Ottawa Scale (NOS) for risk of bias assessment.
resultsNine studies (6,483 hips analyzed with SSM) were included in this review. The SSM models used to describe hip shape ranged from 16 points on the femoral head to 85 points on the proximal femur and hemipelvis. Multiple hip shape features and combinations thereof were associated with incident or progressive hip OA. Shape variants that seemed to be consistently associated with hip OA across studies were acetabular dysplasia, cam morphology, and deviations in acetabular version (either excessive anteversion or retroversion).
conclusionsVarious radiographic, SSM-defined hip shape features are associated with hip OA. Some hip shape features only seem to increase the risk for hip OA when combined together. The heterogeneity of the used SSM models across studies precludes the estimation of pooled effect sizes. Further studies using the same SSM model and definition of hip OA are needed to allow for the comparison of outcomes across studies, and to validate the found associations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.