SynthesisProgress in neuro-psychopharmacology & biological psychiatry2021
Prevalence of anxiety in the COVID-19 pandemic: An updated meta-analysis of community-based studies.
Synthesis in Progress in neuro-psychopharmacology & biological psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 201 papers, 17 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
201 citing papers in PubMed, 17 syntheses or guidelines pooled it, 433 citations in OpenAlex.
- Comparative efficacy of various exercise types and doses for anxiety in older adults: A network and dose-response meta-analysis.BMC geriatrics · 2026Pooled it
- Hospital Anxiety and Depression Scale Anxiety subscale (HADS-A) for detecting anxiety disorders in adults.The Cochrane database of systematic reviews · 2025Pooled it
- The medial prefrontal cortex as a proposed regulatory structure in the relationship between anxiety and perceived social support: a review.BMC psychology · 2025Pooled it
- Death Anxiety Associated With Coronavirus (COVID-19) Disease: A Systematic Review and Meta-Analysis.Omega · 2024Pooled it
- Pooled it
- Prevalence and factors associated with depression, anxiety and stress in Malaysia during COVID-19 pandemic: A systematic review.PloS one · 2023Pooled it
- Prevalence of anxiety during the COVID-19 pandemic: A systematic review and meta-analysis of over 2 million people.Journal of affective disorders · 2022Pooled it
- Alcohol Mixed with Energy Drinks (AmED) Use among University Students: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Gender and COVID-19 related fear and anxiety: A meta-analysis.Journal of affective disorders · 2022Pooled it
- The Acute Impact of the Early Stages of COVID-19 Pandemic in People with Pre-Existing Psychiatric Disorders: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Anxiety Linked to COVID-19: A Systematic Review Comparing Anxiety Rates in Different Populations.International journal of environmental research and public health · 2022Pooled it
- Mental Health Among Medical Students During COVID-19: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2022Pooled it
- Prevalence of anxiety, depressive and insomnia symptoms among the different groups of people during COVID-19 pandemic: An overview of systematic reviews and meta-analyses.Frontiers in psychology · 2022Pooled it
- Prevalence of Anxiety in University Students during the COVID-19 Pandemic: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Prevalence of Anxiety in Dental Students during the COVID-19 Outbreak: A Meta-Analysis.International journal of environmental research and public health · 2021Pooled it
- Prevalence of anxiety in health care professionals during the COVID-19 pandemic: A rapid systematic review (on published articles in Medline) with meta-analysis.Progress in neuro-psychopharmacology & biological psychiatry · 2021Pooled it
- Mental Health in COVID-19 Pandemic: A Meta-Review of Prevalence Meta-Analyses.Frontiers in psychology · 2021Pooled it
- Efficacy of a single session mindfulness based intervention: A randomized clinical trial.PloS one · 2024Trial
- Fear learning and generalization during pandemic fear: How COVID-19-related anxiety affects classical fear conditioning with traumatic film clips.Journal of psychiatric research · 2022Trial
- Effectiveness of a Videoconferencing-Delivered Psychological Intervention for Mental Health Problems during COVID-19: A Proof-of-Concept Randomized Clinical Trial.Psychotherapy and psychosomatics · 2022Trial
141 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe unprecedented worldwide crisis caused by the rapid spread of COVID-19 and the restrictive public health measures enforced by some countries to slow down its transmission have severely threatened the physical and mental wellbeing of communities globally.
methodsWe conducted a systematic review and meta-analysis to determine the prevalence of anxiety in the general population during the COVID-19 pandemic. Two researchers independently searched for cross-sectional community-based studies published between December 1, 2019 and August 23, 2020, using PubMed, WoS, Embase, and other sources (e.g., grey literature, manual search).
resultsOf 3049 records retrieved, 43 studies were included. These studies yielded an estimated overall prevalence of anxiety of 25%, which varied significantly across the different tools used to measure anxiety. Consistently reported risk factors for the development of anxiety included initial or peak phase of the outbreak, female sex, younger age, marriage, social isolation, unemployment and student status, financial hardship, low educational level, insufficient knowledge of COVID-19, epidemiological or clinical risk of disease and some lifestyle and personality variables.
conclusionsAs the overall global prevalence of anxiety disorders is estimated to be 7.3% normally, our results suggest that rates of anxiety in the general population could be more than 3 times higher during the COVID-19 pandemic. These findings suggest a substantial impact on mental health that should be targeted by individual and population-level strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.