Evidence map›Paper›PMID 33338404›Full record

ArticleMolecular cell2020

ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS.

Kevin Rhine, Monika A Makurath, James Liu, Sophie Skanchy, Christian Lopez, Kevin F Catalan, Ye Ma, Charlotte M Fare, James Shorter, Taekjip Ha and 2 more

Abstract readPublished Erratum
In one paragraph

Article in Molecular cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Frontiers in neuroscience · 2023
    Review
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Kevin Rhine
Monika A Makurath
James Liu
Sophie Skanchy
Christian Lopez
Kevin F Catalan
Ye Ma
Charlotte M Fare
James Shorter
Taekjip Ha
Yann R Chemla
Sua Myong

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
Single Molecule Studies of Nucleic Acids RemodelingR35GM122569 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Taekjip Ha · 2017 to 2026
$3.5M
Molecular Assembly and Disassembly of RNA-Protein Complexes Implicated in ALS/FTDRF1NS113636 · NINDS · JOHNS HOPKINS UNIVERSITY · PI MYONG, SUA · 2019 to 2019
$2.0M
Mechanisms of regulation of DNA repair helicasesR01GM120353 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHEMLA, YANN R. · 2016 to 2020
$1.4M
Elucidating the molecular mechanism underlying ALS/FTD-linked FUS mutations with single-molecule resolutionF31NS113439 · NINDS · JOHNS HOPKINS UNIVERSITY · PI RHINE, KEVIN · 2020 to 2021
$92k
NIGMS NIH HHS R01 GM120353NIGMS NIH HHS R35 GM122569NIGMS NIH HHS T32 GM007231NINDS NIH HHS F31 NS113439NINDS NIH HHS RF1 NS113636
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID33338404
PMCPMC7788473

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.