Evidence map›Paper›PMID 33338116›Full record

ArticleRevista da Sociedade Brasileira de Medicina Tropical2020

Reactivation of Chagas disease after autologous hematopoietic stem cell transplantation.

Claudia Marcela Chalela, Angela Maria Peña, Angela Maria Roa, David L Reyes, Jennifer Paola Rueda, Luis Antonio Salazar, Manuel Rosales, Edgar David Gomez, Edgar Augusto Bernal, Claudia Lucia Sossa Melo

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Revista da Sociedade Brasileira de Medicina Tropical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Chagas disease in immunocompromised patients.Clinical microbiology reviews · 2024
    Review
  2. Article
  3. Current tropical medicine reports · 2023
    Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Claudia Marcela ChalelaUniversidad Autónoma de Bucaramanga, Faculty of Health Sciences, Bucaramanga, Santander, Colombia.
Angela Maria PeñaUniversidad Autónoma de Bucaramanga, Faculty of Health Sciences, Bucaramanga, Santander, Colombia.
Angela Maria RoaUniversidad Autónoma de Bucaramanga, Faculty of Health Sciences, Bucaramanga, Santander, Colombia.
David L ReyesUniversidad Autónoma de Bucaramanga, Faculty of Health Sciences, Bucaramanga, Santander, Colombia.
Jennifer Paola RuedaUniversidad Autónoma de Bucaramanga, Faculty of Health Sciences, Bucaramanga, Santander, Colombia.
Luis Antonio SalazarUniversidad Autónoma de Bucaramanga, Faculty of Health Sciences, Bucaramanga, Santander, Colombia.
Manuel RosalesClínica FOSCAL, Hematopoietic and Stem Cell Transplantation Unit, Floridablanca, Santander, Colombia.
Edgar David GomezUniversidad Autónoma de Bucaramanga, Faculty of Health Sciences, Bucaramanga, Santander, Colombia.
Edgar Augusto BernalClínica FOSCAL, Department of Infectious Diseases, Floridablanca, Santander, Colombia.
Claudia Lucia Sossa MeloUniversidad Autónoma de Bucaramanga, Faculty of Health Sciences, Bucaramanga, Santander, Colombia.ORCID http://orcid.org/0000-0001-9876-222X
Universidad Autónoma de Bucaramanga · COFoscal Hospital · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease (CD) is a protozoan zoonosis caused by Trypanosoma cruzi. Reactivation of CD occurs via drug-induced immunosuppression before and during transplantation. Here, we report the case of a 62-year-old man diagnosed with classic Hodgkin lymphoma who received highly aggressive conditioning chemotherapy before undergoing stem cell transplantation (SCT). The patient tested positive for CD in pre-transplantation evaluation. The patient exhibited persistent fever and elevated C-reactive protein levels before and after SCT, and was treated with antibiotics. Micro-Strout test showed evidence of trypomastigotes and he was treated with benznidazole until tested negative. Post-transplantation seropositive patients should be screened for possible reactivation.

Indexed as

Chagas DiseaseHematopoietic Stem Cell TransplantationTrypanosoma cruziAnimalsHumansImmunosuppression TherapyMaleMiddle AgedZoonoses

Identifiers

PMID33338116
PMCPMC7747816
OpenAlexW3115485897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.