Evidence map›Paper›PMID 33337618›Full record

ReviewCurrent opinion in infectious diseases2021

Nonviral sexually transmitted infections in pregnancy: current controversies and new challenges.

Andreea Waltmann, Tyler R McKinnish, Joseph A Duncan

Abstract readReview
In one paragraph

Review in Current opinion in infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Prevalence ofEpidemiology and infection · 2025
    Article
  2. Current Evidence of Maternal Infection With Chlamydia trachomatis and Preeclampsia Risk.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025
    Review
  3. Article
  4. Experimental Urethral Infection with Neisseria gonorrhoeae.Current topics in microbiology and immunology · 2024
    Review
  5. The Impact ofOpen forum infectious diseases · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andreea WaltmannInstitute for Global Health and Infectious Disease, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Tyler R McKinnishDepartment of Obstetrics and Gynecology, Washington University in St. Louis, St Louis, Missouri.
Joseph A DuncanDivision of Infectious Diseases, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Funding

The Gonorrhea Vaccine Cooperative Research CenterU19AI144180 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI SIKORA, ALEKSANDRA ELZBIETA · 2019 to 2023
$10.7M
Hemodynamics and Vascular Wall Biology Determine Arteriovenous Fistula MaturationR01DK088777 · NIDDK · UNIVERSITY OF UTAH · PI BERCELI, SCOTT A, CHEUNG, ALFRED K · 2011 to 2014
$2.6M
Localized Delivery of Sirolimus to Hemodialysis Vascular Access GraftsR44AG059279 · NIA · CYLERUS, INC. · PI ROY-CHAUDHURY, PRABIR, SHEBUSKI, RONALD J. · 2017 to 2019
$1.7M
Clinical, Hemodynamic and Biological Markers of AV Fistula MaturationU01DK082218 · NIDDK · UNIVERSITY OF CINCINNATI · PI ROY-CHAUDHURY, PRABIR · 2008 to 2012
$1.7M
North Carolina Translational and Clinical Science Institute (NC TraCS) TL1TL1TR002491 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ROY-CHAUDHURY, PRABIR · 2018 to 2022
$1.5M
A luminal vascular coating to reduce time to maturation and failures of AV-Fistulas for hemodialysis accessR44DK100156 · NIDDK · SYMIC BIOMEDICAL, INC. · PI KATHERINE STUART, KATHERINE STUART, ROY-CHAUDHURY, PRABIR · 2015 to 2016
$1.5M
Antiproliferative Rx for venous neointimal hyperplasiaR01DK061689 · NIDDK · UNIVERSITY OF CINCINNATI · PI ROY-CHAUDHURY, PRABIR · 2002 to 2005
$1.2M
Transforming Kidney Care through Skill and Workforce Development: the North Carolina Kidney Technology Incubator (NC-KTI)R25DK131344 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Theo Dingemans, Caterina M Gallippi · 2022 to 2026
$527k
Reducing Tunneled Dialysis Catheter Dysfunction through Nitric Oxide ReleaseR21EB016737 · NIBIB · UNIVERSITY OF CINCINNATI · PI MEYERHOFF, MARK E, ROY-CHAUDHURY, PRABIR · 2013 to 2014
$450k
Real Time Nitric Oxide Measurements as a Determinant of AV Fistula MaturationR21DK089280 · NIDDK · UNIVERSITY OF CINCINNATI · PI ROY-CHAUDHURY, PRABIR · 2010 to 2011
$424k
Biodegradable Magensium Stents to Enhance AV Fistula MaturationR21EB016150 · NIBIB · UNIVERSITY OF CINCINNATI · PI ROY-CHAUDHURY, PRABIR · 2012 to 2013
$419k
Dialysis access monitoring using a digital stethoscope-based deep learning systemR43DK129107 · NIDDK · EKO DEVICES, INC. · PI ROY-CHAUDHURY, PRABIR, VENKATRAMAN, SUBRAMANIAM · 2021 to 2021
$299k
BLRD VA I01 BX002390NCATS NIH HHS TL1 TR002491NHLBI NIH HHS R41 HL151235NIAID NIH HHS U19 AI144180NIA NIH HHS R44 AG059279NIBIB NIH HHS R21 EB016150NIBIB NIH HHS R21 EB016737NIDDK NIH HHS R01 DK061689NIDDK NIH HHS R01 DK088777NIDDK NIH HHS R21 DK089280NIDDK NIH HHS R25 DK131344NIDDK NIH HHS R41 DK101206NIDDK NIH HHS R41 DK111332NIDDK NIH HHS R43 DK129107NIDDK NIH HHS R44 DK100156NIDDK NIH HHS U01 DK082218
6 · The paper itself

Abstract

purpose of reviewThis review provides an update of nonviral, curable sexually transmitted infections (STIs) in pregnancy and summarizes our understanding of the current issues and controversies surrounding risk factors, screening, and treatment of STIs in pregnancy primarily in high-income countries (using the United States and the United Kingdom as examples). The infections covered in this review are syphilis, gonorrhea, chlamydia, trichomoniasis, and Mycoplasma genitalium infections. RECENT

findingsOverall, limited modern data is available to update researchers and clinicians on the epidemiology and care of STIs in pregnancy. Though common risk factors can be identified among these STIs, like socioeconomic status and inadequate antenatal care, specific screening and treatment challenges vary by geography and pathogen. Wherever available, surveillance data and research evidence are often limited to nonpregnant patients, leading to imperfect pregnancy-specific risk estimates and obstetric lags in the development and adoption of new guidelines. We have identified three areas of opportunity that may enhance the effectiveness of current approaches and inform new ones: improved data collection and evidence-based screening practices; prompt and comprehensive therapy, including partner services, and evaluations of new treatment modalities; and equitable antenatal and sexual healthcare for all pregnant persons and their partners. SUMMARY: These findings highlight the need to revisit standards of screening and management of STIs in pregnancy in high-income countries.

Indexed as

FemaleHumansPregnancyPregnancy Complications, InfectiousSexually Transmitted DiseasesUnited KingdomUnited States

Identifiers

PMID33337618
PMCPMC8634851

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.