Evidence map›Paper›PMID 33336898›Full record

ArticleMicrobial biotechnology2022

A structurally unique Fusobacterium nucleatum tannase provides detoxicant activity against gallotannins and pathogen resistance.

José Miguel Mancheño, Estíbaliz Atondo, Julen Tomás-Cortázar, José Luís Lavín, Laura Plaza-Vinuesa, Itziar Martín-Ruiz, Diego Barriales, Ainhoa Palacios, Claudio Daniel Navo, Leticia Sampedro and 14 more

Open access · goldAbstract read
In one paragraph

Article in Microbial biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Biochemical and Structural Characterization of a Novel Bacterial Tannase FromFrontiers in bioengineering and biotechnology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 6 institutions in 2 countries.

José Miguel MancheñoDepartamento de Cristalografía y Biología Estructural, Instituto de Química-Física "Rocasolano" (IQFR-CSIC), Madrid, 28006, Spain.ORCID 0000-0001-6943-3291
Estíbaliz AtondoInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.
Julen Tomás-CortázarInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.
José Luís LavínBioinformatics Unit, CIC bioGUNE-BRTA, Bizkaia Technology Park, Derio, Bizkaia, 48160, Spain.ORCID 0000-0003-0914-3211
Laura Plaza-VinuesaLaboratorio de Biotecnología Bacteriana, Instituto de Ciencia y Tecnología de los Alimentos y Nutrición (ICTAN)-Consejo Superior de Investigaciones Científicas (CSIC), Madrid, 28006, Spain.
Itziar Martín-RuizInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.
Diego BarrialesInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.ORCID 0000-0002-6433-3379
Ainhoa PalaciosInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.ORCID 0000-0001-8945-5260
Claudio Daniel NavoComputational Chemistry lab, CIC bioGUNE-BRTA, Derio, 48160, Spain.ORCID 0000-0003-0161-412X
Leticia SampedroInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.
Ainize Peña-CearraInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.ORCID 0000-0003-3855-6664
Miguel Ángel Pascual-ItoizInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.
Janire CasteloInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.
Ana Carreras-GonzálezInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.
Donatello CastellanaResearch & Development, CIC bioGUNE-BRTA, Derio, 48160, Spain.ORCID 0000-0002-8263-8467
Aize PellónInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.ORCID 0000-0003-0415-6566
Susana DelgadoDairy Research Institute, Spanish National Research Council (Instituto de Productos Lácteos de Asturias - CSIC), Asturias, 33300, Spain.ORCID 0000-0002-1081-2614
Patricia Ruas-MadiedoDairy Research Institute, Spanish National Research Council (Instituto de Productos Lácteos de Asturias - CSIC), Asturias, 33300, Spain.ORCID 0000-0001-6158-9320
Blanca de Las RivasLaboratorio de Biotecnología Bacteriana, Instituto de Ciencia y Tecnología de los Alimentos y Nutrición (ICTAN)-Consejo Superior de Investigaciones Científicas (CSIC), Madrid, 28006, Spain.ORCID 0000-0002-8357-5226
Leticia AbeciaInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.ORCID 0000-0003-4097-8903
Rosario MuñozLaboratorio de Biotecnología Bacteriana, Instituto de Ciencia y Tecnología de los Alimentos y Nutrición (ICTAN)-Consejo Superior de Investigaciones Científicas (CSIC), Madrid, 28006, Spain.
Gonzalo Jiménez-OsésComputational Chemistry lab, CIC bioGUNE-BRTA, Derio, 48160, Spain.ORCID 0000-0003-0105-4337
Juan AnguitaInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.ORCID 0000-0003-2061-7182
Héctor RodríguezInflammation and Macrophage Plasticity lab, CIC bioGUNE-BRTA (Basque Research and Technology Alliance), Derio, 48160, Spain.ORCID 0000-0002-9948-2497
CIC bioGUNE · ESConsejo Superior de Investigaciones Científicas · ESUniversity of the Basque Country · ESIkerbasque · ESInstituto de Química Física Blas Cabrera · ESUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer pathogenesis and progression is associated with the presence of Fusobacterium nucleatum and the reduction of acetylated derivatives of spermidine, as well as dietary components such as tannin-rich foods. We show that a new tannase orthologue of F. nucleatum (TanBF

Indexed as

Fusobacterium nucleatumHydrolyzable TanninsCarboxylic Ester HydrolasesSpermidineCarboxylic Ester HydrolasesHydrolyzable TanninsSpermidinetannase

Identifiers

PMID33336898
PMCPMC8867971
OpenAlexW3112300022

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.