Evidence map›Paper›PMID 33336860›Full record

ArticleJournal of veterinary internal medicine2021

Identification of 5 novel feline erythrocyte antigens based on the presence of naturally occurring alloantibodies.

Marie Binvel, Julie Arsenault, Boris Depré, Marie-Claude Blais

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  4. Evaluation of the utility and accuracy of body fluids containing red blood cells to determine canine and feline blood types.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2023
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  8. Wild Felids Blood Group System.Animals : an open access journal from MDPI · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Marie BinvelDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Université de Montréal, Saint-Hyacinthe, Canada.ORCID https://orcid.org/0000-0002-8911-1465
Julie ArsenaultDepartment of Pathology and Microbiology, Faculty of Veterinary Medicine, Université de Montréal, Saint-Hyacinthe, Canada.ORCID https://orcid.org/0000-0001-8382-7326
Boris DepréEmergency and Critical Care, Adomvet, Lyon, France.
Marie-Claude BlaisDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Université de Montréal, Saint-Hyacinthe, Canada.
Cegep de Saint Hyacinthe · CALaboratoire Aménagement Économie Transports · FR

Funding

Companion Animals Health Fund from the Faculty of Veterinary Medicine of the Université de Montréal, supported by Zoetis
6 · The paper itself

Abstract

backgroundSince the discovery of the Mik antigen, several studies have described blood incompatibilities unrelated to the AB system in cats.

objectiveTo estimate the prevalence of cats with non-AB incompatibilities associated with naturally occurring alloantibodies (NOAb), and to begin mapping the corresponding feline erythrocyte antigens (FEA). ANIMALS: Two hundred and fifty-eight type A cats.

methodsProspectively, cats were evaluated for the presence of NOAb by crossmatching in groups of 4-6 cats. When NOAb were detected in a cat, its plasma was used as reagent to assess for the presence of the corresponding FEA in all cats included thereafter, and agreement observed between results of this extensive blood typing was evaluated.

resultsThe chance of detecting incompatibilities by randomly crossmatching 2 cats was 3.9%, which resulted in at least 7% of type A cats having NOAb. Blood typing and agreement analyses performed with 7 newly detected NOAb allowed the identification of 5 presumably distinct FEA. Feline erythrocyte antigens 1 and 5 were most frequent with prevalence of 84% and 96%, respectively. Only FEA 1-negative status was associated with a higher risk of presenting NOAb; with 16.7% of 42 FEA 1-negative cats having NOAb compared to 5.1% of 216 FEA 1-positive cats. CONCLUSIONS AND CLINICAL IMPORTANCE: This study represents a first step of FEA identification outside the AB system. Because of its prevalence and association with NOAb, FEA 1 might correspond to the Mik antigen.

Indexed as

Blood Group AntigensIsoantibodiesAnimalsBlood Grouping and CrossmatchingCatsErythrocytesPrevalenceBlood Group AntigensIsoantibodiesalloimmunisationblood compatibilityblood typingcrossmatchMik antigentransfusion

Identifiers

PMID33336860
PMCPMC7848337
OpenAlexW3117706066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.