Evidence map›Paper›PMID 33336704›Full record

ArticlePhysical therapy2021

Can the ARAT Be Used to Measure Arm Function in People With Cerebellar Ataxia?

Rachel Reoli, Kendra Cherry-Allen, Amanda Therrien, Jennifer Keller, Kristan Leech, Abigail Leddy Whitt, Amy Bastian

Open access · bronzeAbstract readValidation Study
In one paragraph

Article in Physical therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Rachel ReoliDepartment of Physical Medicine and Rehabilitation, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Kendra Cherry-AllenDepartment of Physical Medicine and Rehabilitation, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Amanda TherrienDivision of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, California, USA.
Jennifer KellerCenter for Movement Studies, Kennedy Krieger Institute, Baltimore, Maryland, USA.
Kristan LeechMoss Rehabilitation Research Institute, Elkins Park, Pennsylvania, USA.
Abigail Leddy WhittInova Fairfax Hospital Health System, Fairfax, Virginia, USA.
Amy BastianDepartment of Physical Medicine and Rehabilitation, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Kennedy Krieger Institute · USInova Fairfax Hospital · USMoss Rehabilitation Hospital · USNephrology Center of Maryland · USUniversity of Maryland, Baltimore · USUniversity of Southern California · US

Funding

Sleep and Circadian Dysfunction, Brain and Neurobehavioral Development in AutismP50HD103538 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI S. Ali Fatemi, Bradley L Schlaggar · 2020 to 2026
$9.9M
Research Training in Rehabilitation for Brain Injury and Neurological DisabilityT32HD007414 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Amy J. Bastian · 1991 to 2026
$6.3M
MECHANISMS AND REHABILITATION OF CEREBELLAR ATAXIAR01HD040289 · NICHD · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI BASTIAN, AMY J. · 2002 to 2022
$6.2M
NICHD NIH HHS P50 HD103538NICHD NIH HHS R01 HD040289NICHD NIH HHS T32 HD007414
6 · The paper itself

Abstract

objectiveFor people with ataxia, there are validated outcome measures to address body function and structure (BFS) impairments and participation; however, no outcome measure exists for upper extremity (UE) activity level in this population. The purpose of this study was to determine whether the action research arm test (ARAT), a measure of UE activity validated for other neurological conditions, might be a useful outcome measure for capturing UE activity limitations in ataxia.

methodsA total of 22 participants with ataxia were evaluated to assess construct validity of the ARAT; 19 of the participants were included in the interrater reliability assessment. Participants received a neurologic examination and completed a battery of outcome measures, including the ARAT. ARAT performance was video recorded and scored by 4 additional raters.

resultsFor construct validity, Spearman rho showed a significant moderate relationship between the ARAT and BSF outcome measures. A small, nonsignificant relationship was noted for the ARAT and the participation measure. For interrater reliability, Spearman rho showed a large, significant relationship among all raters for the ARAT (range = .87-.94). High reliability was demonstrated using the intraclass correlation coefficient ([2,1] = .97).

conclusionThe ARAT is moderately correlated with ataxia BFS outcome measures, but not with participation scores. The ARAT is a measure of UE activity, which is different from BFS and participation outcome measures. The ARAT was identified to have strong interrater reliability among raters with varying amounts of experience administering the ARAT. Thus, for the ataxic population, the ARAT may be useful for assessing UE activity limitations. IMPACT: Ataxia can negatively affect reaching tasks; therefore, it is important to assess UE activity level in people with ataxia. Until this study, no outcome measure had been identified for this purpose. LAY SUMMARY: People with ataxia may have difficulty with daily tasks that require reaching. The ARAT is an outcome measure that clinicians can use to assess UE activity limitations to help design a treatment program.

Indexed as

AdultAgedCerebellar AtaxiaHand StrengthHumansMiddle AgedNeurologic ExaminationOutcome Assessment, Health CareReproducibility of ResultsUpper ExtremityYoung AdultActivities of Daily Living)AtaxiaInternational Classification of DiseasesOutcome Assessment (Health CareRehabilitationStatistics

Identifiers

PMID33336704
PMCPMC7899061
OpenAlexW3115673368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.