Evidence map›Paper›PMID 33336176›Full record

ArticleWorld journal of otorhinolaryngology - head and neck surgery2020

The impact of endoscopic sinus surgery and aspirin desensitization on psychological burden in aspirin-exacerbated respiratory disease.

Tran Locke, Auddie Sweis, Theodore Lin, Brian Sweis, Patrick Gleeson, Michael Kohanski, Nithin Adappa, James Palmer, John Bosso

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of otorhinolaryngology - head and neck surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. AERD: Quo Vadis?World journal of otorhinolaryngology - head and neck surgery · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Tran LockeDepartment of Otolaryngology, Baylor College of Medicine, Houston, TX, USA.
Auddie SweisDivision of Otolaryngology, NorthShore University Health System, Evanston, IL, USA.
Theodore LinLewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Brian SweisDepartment of Neuroscience, University of Minnesota, Minneapolis, MN, USA.
Patrick GleesonDepartment of Allergy & Immunology, University of Pennsylvania, Philadelphia, PA, USA.
Michael KohanskiDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, USA.
Nithin AdappaDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, USA.
James PalmerDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, USA.
John BossoDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · USBaylor College of Medicine · USNorthShore University HealthSystem · USTemple University · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAspirin-exacerbated respiratory disease (AERD) is an aggressive inflammatory disorder of the upper and lower respiratory tract. Corticosteroids, leukotriene modifiers, endoscopic sinus surgery (ESS), aspirin (ASA) desensitization, and biological immunomodulators are currently used to treat the disorder.

objectiveThe objective of this study was to determine the psychosocial impact of ESS and ASA desensitization on AERD patients.

methodsAll AERD patients who underwent complete ESS were divided into two cohorts based on ASA desensitization status. The psychosocial metrics of the SNOT-22 were collected and analyzed at the following time points: pre-operative, 1-month, 3-month, 6-month, and 12-month after ESS.

resultsOne hundred and eighty-four AERD patients underwent ESS from November 2009 to November 2018. From this group, 130 patients underwent ASA desensitization (AD cohort) and 54 patients remained non-desensitized (ND cohort). AD patients showed a significantly greater reduction in total SNOT-22 scores over the study period compared to ND patients (

conclusionsESS followed by ASA desensitization decreases the overall psychosocial burden in AERD patients with a significant improvement in perceived productivity and concentration. This has significant implications given the psychosocial impact of chronic diseases.

Indexed as

AERDAspirin desensitizationPsychosocial domainSinus surgery

Identifiers

PMID33336176
PMCPMC7729229
OpenAlexW3093604231

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.