Evidence map›Paper›PMID 33336068›Full record

ArticleOpen medicine (Warsaw, Poland)2020

Serum calcium levels correlates with coronary artery disease outcomes.

Mian Wang, Shaodi Yan, Yong Peng, Yu Shi, Jiay-Yu Tsauo, Mao Chen

Open access · goldAbstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Mian WangDepartment of Cardiology, Fuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, Shenzhen, 518057, China.
Shaodi YanDepartment of Cardiology, West China Hospital, Sichuan University, No. 37, Guoxue Street, Chengdu, 610041, China.
Yong PengDepartment of Cardiology, West China Hospital, Sichuan University, No. 37, Guoxue Street, Chengdu, 610041, China.
Yu ShiFuwai Hospital Chinese Academy of Medical Sciences, Shenzhen, Shenzhen, 518057, Guangdong Province, China.
Jiay-Yu TsauoDepartment of Cardiology, West China Hospital, Sichuan University, No. 37, Guoxue Street, Chengdu, 610041, China.
Mao ChenDepartment of Cardiology, West China Hospital, Sichuan University, No. 37, Guoxue Street, Chengdu, 610041, China.
Sichuan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEffect of serum calcium levels on prognosis of patients with coronary artery disease (CAD) is not well evaluated. We aimed to assess the associations of baseline serum calcium levels with both short-term and long-term outcomes in CAD patients.

methodsThis study included 3,109 consecutive patients with angiographically confirmed CAD. Patients were categorized into quartiles according to admission serum calcium. Multivariable regression analysis was used to determine the association of serum calcium with mortality.

resultsCompared to patients in the lowest quartile of serum calcium, patients in upper quartiles were presented with lower all-cause mortality (Hazard ratios [HRs] were -0.636 [95% CI: -0.424 to -0.954], -0.545 [95% CI: -0.351 to -0.846] and -0.641 [95% CI: -0.450 to -0.913] for three upper quartiles versus lowest quartile respectively), cardiovascular mortality (HRs 0.594 [0.368-0.961], 0.261 [0.124-0.551] and 0.407 [0.229-0.725]), and in-hospital mortality (Odd ratios [ORs] 0.391 [0.188-0.812], 0.231 [0.072-0.501] and 0.223 [0.093-0.534]). Consistent associations between serum calcium and long-term mortality were also obtained in subgroup analysis of ACS patients, stable CAD patients and discharged patients.

conclusionsSerum calcium is inversely associated with CAD and can independently predict both in-hospital and long-term mortality among CAD patients.

Indexed as

coronary artery diseaseindependent predictorprognosisserum calcium

Identifiers

PMID33336068
PMCPMC7718611
OpenAlexW3098909642

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.