ArticleOpen medicine (Warsaw, Poland)2020
Prognostic factors in stage I gastric cancer: A retrospective analysis.
Article in Open medicine (Warsaw, Poland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 34 citations in OpenAlex.
- Survival Impact of Adjuvant Chemotherapy on Stage IB Gastric Cancer Patients After Radical Surgery.Journal of gastrointestinal cancer · 2026Article
- Prognostic factors and adjuvant chemotherapy efficacy in stage I gastric cancer patients: a retrospective analysis.BMC gastroenterology · 2024Article
- Identification and validation of the role of ZNF281 in 5-fluorouracil chemotherapy of gastric cancer.Journal of cancer research and clinical oncology · 2024Article
- A Cost-Effective Model for Predicting Recurrent Gastric Cancer Using Clinical Features.Diagnostics (Basel, Switzerland) · 2024Article
- Risk stratification for predicting postoperative recurrence of gastric cancer by grade of venous invasion.BMC gastroenterology · 2023Article
- Tumor size as a significant prognostic factor in T1 gastric cancer: a Surveillance, Epidemiology, and End Results (SEER) database analysis.BMC gastroenterology · 2023Article
- Association between adjuvant chemotherapy and survival in stage I gastric cancer patients after curative resection.Gastroenterology report · 2023Article
- Clinical significance of the largest histopathological metastatic lymph node size for postoperative course of patients undergoing surgery for gastric cancer.Frontiers in surgery · 2023Article
- Impact of Clinicopathological Features on Gastric Cancer Stage According to TNM Classification.In vivo (Athens, Greece)Article
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9 authors at 4 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this research is to investigate the prognostic factors of patients with stage I gastric cancer (GC) and to determine whether adjuvant chemotherapy improves the prognosis for high-risk patients.
methodsWe performed a retrospective analysis at Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, and HwaMei Hospital, University of Chinese Academy of Sciences from January 2001 to December 2015. Cox regression and Kaplan-Meier were used to evaluate the relationship between the patients' clinicopathologic characteristics and prognosis.
resultsA total of 1,550 patients were eligible for the study. The 5-year disease-free survival (DFS) rate of all enrolled patients was 96.5%. The pT and pN stages were significantly associated with the prognosis. The 5-year DFS rates of the three subgroups (T1N0, T2N0, and T1N1) were 97.8%, 95.7%, and 90.5%, respectively (
conclusionsBoth the pT and pN stages were closely associated with the prognosis of patients with stage I GC. We also found that the danger coefficient of the pN stage was higher than that of the pT stage, and that postoperative adjuvant chemotherapy might be a reasonable approach to improve outcomes of high-risk patients, particularly in the T1N1 group.
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