Evidence map›Paper›PMID 33336030›Full record

ArticleOpen medicine (Warsaw, Poland)2020

Clinical significance and potential mechanisms of

Lei Zhao, Congzhe Tian, Erbin Xiao, Jinduo Du, Jingwei Liang, Xianghong Chen, Weiwei Chi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open medicine (Warsaw, Poland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Linc-ROR Promotes EMT by Targeting miR-204-5p/SMAD4 in Endometriosis.Reproductive sciences (Thousand Oaks, Calif.) · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lei ZhaoDepartment of Otorhinolaryngology, The Affiliated Hospital of Hebei University, Baoding, No. 212 Yuhua Road, Hebei Province, 071000, China.
Congzhe TianDepartment of Otorhinolaryngology, The Affiliated Hospital of Hebei University, Baoding, No. 212 Yuhua Road, Hebei Province, 071000, China.
Erbin XiaoDepartment of Otorhinolaryngology, The Affiliated Hospital of Hebei University, Baoding, No. 212 Yuhua Road, Hebei Province, 071000, China.
Jinduo DuDepartment of Otorhinolaryngology, The Affiliated Hospital of Hebei University, Baoding, No. 212 Yuhua Road, Hebei Province, 071000, China.
Jingwei LiangDepartment of Otorhinolaryngology, The Affiliated Hospital of Hebei University, Baoding, No. 212 Yuhua Road, Hebei Province, 071000, China.
Xianghong ChenDepartment of Otorhinolaryngology, The Affiliated Hospital of Hebei University, Baoding, No. 212 Yuhua Road, Hebei Province, 071000, China.
Weiwei ChiDepartment of Otorhinolaryngology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, 050031, China.
Affiliated Hospital of Hebei University · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the clinical significance and mechanisms of altered miRNAs in squamous cell carcinoma of head and neck (SCCHN) and provide references for SCCHN diagnosis and prognosis.

methodDifferential expressed miRNAs (DEMs) in SCCHN were screened through gene expression omnibus (GEO) DataSets and verified by the cancer genome atlas (TCGA) database. Next, the overall survival analysis, receiver operating characteristics, and clinical correlation analysis were adopted to filter the miRNAs with diagnostic and prognostic values. Finally, functional enrichment analyses were conducted for inquiring into the mechanisms of miRNAs.

resultsTotal 103 DEMs (

conclusionWith diagnostic and prognostic values,

Indexed as

head and neck tumormiR-204-5pmiR-223-3pmiRNASCCHN

Identifiers

PMID33336030
PMCPMC7712329
OpenAlexW3056961641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.