Evidence map›Paper›PMID 33335982›Full record

ArticleTransplantation direct2021

Biliary Strictures Are Associated With Both Early and Late Hepatic Artery Stenosis.

Angus Hann, Rashmi Seth, Hynek Mergental, Hermien Hartog, Mohammad Alzoubi, Arie Stangou, Omar El-Sherif, James Ferguson, Keith Roberts, Paolo Muiesan and 4 more

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Angus HannLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Rashmi SethLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Hynek MergentalLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Hermien HartogLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Mohammad AlzoubiLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Arie StangouLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Omar El-SherifLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
James FergusonLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Keith RobertsLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Paolo MuiesanLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Ye OoLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
John R IssacLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Darius MirzaLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
M Thamara P R PereraLiver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Queen Elizabeth Hospital Birmingham · GBUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatic artery stenosis (HAS) following liver transplantation results in hypoperfusion and ischemic damage to the biliary tree. This study aimed to investigate how vascular intervention, liver function test derangement, and time point of HAS onset influence biliary complications.

methodsA single-center retrospective study of adult patients that underwent primary liver transplantation. Patients were grouped according to the presence or absence of HAS and then into early (≤90 d) or late (>90 d) subgroups. Biliary complications comprised anastomotic (AS) or non ASs (NASs).

resultsComputed tomography angiography confirmed HAS was present in 39 of 1232 patients (3.2%). This occurred at ≤90 and >90 days in 20 (1.6%) and 19 (1.5%), respectively. The incidence of biliary strictures (BSs) in the group with HAS was higher than the group without (13/39; 33% versus 85/1193; 7.1%,

conclusionsBS occurs at a significantly higher rate in the presence of HAS. Onset of HAS at ≤90 or ≥90 days can both be associated with morbidity. Significant liver function test derangement at HAS diagnosis indicates a higher likelihood of biliary intervention for strictures.

Identifiers

PMID33335982
PMCPMC7738047
OpenAlexW3114315794

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.