Evidence map›Paper›PMID 33335953›Full record

ArticleEuropean journal of radiology open2021

Does prophylactic inferior vena cava filter reduce the hazard of pulmonary embolism and mortality in severe trauma? A single center retrospective comparative study.

Thien Trung Tran, Haraldur Bjarnason, Jennifer McDonald, Brian Goss, Brian Kim, Damon E Houghton, Knut Stavem, Nils Einar Kløw

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of radiology open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Thien Trung TranInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.
Haraldur BjarnasonDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Jennifer McDonaldDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Brian GossDepartment of Radiology, Kingman Regional Medical Center, AZ, USA.
Brian KimDivision of Trauma, Critical Care and General Surgery, Mayo Clinic, Rochester, MN, USA.
Damon E HoughtonDepartment of Hematology, Mayo Clinic, Rochester, MN, USA.
Knut StavemInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.
Nils Einar KløwInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.
Mayo Clinic in Arizona · USUniversity of Oslo · NOMayo Clinic · USRegional Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesUse of inferior vena cava (IVC) filters in patients following severe trauma without recent history of venous thromboembolism (VTE) is controversial. Our objective was to determine if IVC filter placement in the setting of severe trauma effects the hazard of in-hospital pulmonary embolism (PE), deep venous thrombosis (DVT) and mortality.

methodsThis retrospective study recruited patients from a single Level I Trauma Center between 1/2008 and 12/2013. Inclusion criteria were age>15 years, Injury Severity Score (ISS)>15 and survival>24 h after hospital admission. Patients with VTE diagnosed prior to IVC filter placement were excluded. A Cox proportional hazards regression model was used, adjusting for immortal time bias with landmark analysis at predefined time after injury. Differences between IVC filter and non-IVC filter groups were adjusted using propensity score.

resultsIn total 1451 patients were reviewed; 282 patients received an IVC filter and 1169 patients had no IVC filter placed. The mean age was 45.9 vs. 56.9 years and the mean ISS was 29.8 vs. 22.6 in the IVC filter and the non-IVC filter group, respectively. IVC filter placement was not associated with the hazard of PE (HR = 0.46; 95 % CI, 0.12,1.70; P = 0.24) or mortality (HR = 1.02; 95 % CI 0.60,1.75; P = 0.93). However, IVC filter placement was associated with the hazard of DVT (HR = 2.73; 95 % CI, 1.28,5.85; P = 0.01).

conclusionsIn patients with severe trauma, those with prophylactic IVC filter placement did not have a reduced hazard of PE or mortality, but an increased hazard of DVT was observed.

Indexed as

AIS, Abbreviated Injury ScaleCritical careDVT, deep venous thrombosisGCS, Glasgow Coma ScaleHR, Hazard RatioInferior vena cava filterISS, Injury Severity ScoreIVC, Inferior Vena CavaMultiple traumaPatient outcomePE, pulmonary embolismPulmonary embolismVenous thromboembolismVTE, venous thromboembolism

Identifiers

PMID33335953
PMCPMC7734225
OpenAlexW3112670903

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.