Evidence map›Paper›PMID 33335802›Full record

ArticleAPL materials2018

Perspective: Aligned arrays of electrospun nanofibers for directing cell migration.

Jiajia Xue, Tong Wu, Younan Xia

Open access · goldAbstract read
In one paragraph

Article in APL materials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
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  4. Article
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  7. Review
  8. Keratin Additive for Cellular Adhesion in Transcutaneous Prosthetics.Journal of tissue engineering and regenerative medicine · 2025
    Article
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  10. Article
  11. Review
  12. Article
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  19. Next Stage Approach to Tissue Engineering Skeletal Muscle.Bioengineering (Basel, Switzerland) · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jiajia XueThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA.ORCID 0000-0002-7209-7935
Tong WuThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA.ORCID 0000-0001-8822-1868
Younan XiaThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, USA.
Georgia Institute of Technology · US

Funding

Nanofiber Conduits with a Honeycomb Structure for Repairing Large Defects in Thick NervesR01EB020050 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI BOULIS, NICHOLAS M, XIA, YOUNAN · 2015 to 2018
$1.7M
NIBIB NIH HHS R01 EB020050
6 · The paper itself

Abstract

Cell migration plays an important role in a wide variety of biological processes, including embryogenesis, wound healing, inflammation, cancer metastasis, and tissue repair. Electrospun nanofibers have been extensively explored as scaffolds to manipulate cell migration owing to their unique characteristics in mimicking the hierarchical architecture of extracellular matrix. In particular, aligned arrays of electrospun nanofibers are capable of guiding and promoting the directional migration of cells. The physical parameters and properties of the aligned nanofibers, including their size, modulus, and surface chemistry, can all affect the migratory behaviors of cells, while the controlled release of growth factors and drugs from the nanofibers can also be utilized to influence cell migration. By manipulating cell migration, electrospun nanofibers have been applied to promote tissue repair and help eradicate tumors

Identifiers

PMID33335802
PMCPMC7743993
OpenAlexW2905449680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.