Evidence map›Paper›PMID 33335790›Full record

ArticleJournal of clinical & cellular immunology2020

Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.

Tuqa Alkhateeb, Isatou Bah, Ajinkya Kumbhare, Dima Youssef, Zhi Q Yao, Charles E McCall, Mohamed El Gazzar

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical & cellular immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tuqa AlkhateebDepartment of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN 37614, USA.
Isatou BahDepartment of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN 37614, USA.
Ajinkya KumbhareDepartment of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN 37614, USA.
Dima YoussefDepartment of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN 37614, USA.
Zhi Q YaoDepartment of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN 37614, USA.
Charles E McCallDepartment of Internal Medicine, Section of Molecular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.
Mohamed El GazzarDepartment of Internal Medicine, East Tennessee State University College of Medicine, Johnson City, TN 37614, USA.
East Tennessee State University · USWake Forest University · US

Funding

S100A9 and MDSC development in sepsis.R35GM131692 · NIGMS · EAST TENNESSEE STATE UNIVERSITY · PI ELGAZZAR, MOHAMED A. · 2019 to 2023
$1.9M
NIGMS NIH HHS R35 GM131692
6 · The paper itself

Abstract

Myeloid-derived suppressor cells (MDSCs) expand during mouse and human sepsis, but the mechanism responsible for this is unclear. We previously reported that nuclear transport of S100A9 protein programs Gr1

Indexed as

Immune responseInflammationMiceMyeloid-derived suppressor cells (MDSCs)Sepsis

Identifiers

PMID33335790
PMCPMC7744002
OpenAlexW3094805395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.