Evidence map›Paper›PMID 33335546›Full record

ArticleNeural plasticity2020

Emergence of Beta Oscillations of a Resonance Model for Parkinson's Disease.

Yaqian Chen, Junsong Wang, Yanmei Kang, Muhammad Bilal Ghori

Abstract read
In one paragraph

Article in Neural plasticity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. B(RAIN)Scientific data · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. New Targets and New Technologies in the Treatment of Parkinson's Disease: A Narrative Review.International journal of environmental research and public health · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yaqian ChenSchool of Mathematics and Statistics, Xi'an Jiaotong University, Xi'an, 710049 Shaanxi Province, China.ORCID 0000-0002-0050-4140
Junsong WangSchool of Biomedical Engineering, Tianjin Medical University, Tianjin 300070, China.
Yanmei KangSchool of Mathematics and Statistics, Xi'an Jiaotong University, Xi'an, 710049 Shaanxi Province, China.ORCID 0000-0001-8608-9242
Muhammad Bilal GhoriSchool of Mathematics and Statistics, Xi'an Jiaotong University, Xi'an, 710049 Shaanxi Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Parkinson's disease, the excess of beta oscillations in cortical-basal ganglia (BG) circuits has been correlated with normal movement suppression. In this paper, a physiologically based resonance model, generalizing an earlier model of the STN-GPe circuit, is employed to analyze critical dynamics of the occurrence of beta oscillations, which correspond to Hopf bifurcation. With the experimentally measured parameters, conditions for the occurrence of Hopf bifurcation with time delay are deduced by means of linear stability analysis, center manifold theorem, and normal form analysis. It is found that beta oscillations can be induced by increasing synaptic transmission delay. Furthermore, it is revealed that the oscillations originate from interaction among different synaptic connections. Our analytical results are consistent with the previous experimental and simulating findings, thus may provide a more systematic insight into the mechanisms underlying the transient beta bursts.

Indexed as

Action PotentialsBasal GangliaBeta RhythmGlobus PallidusHumansModels, NeurologicalNeuronsParkinson DiseaseSynaptic Transmission

Identifiers

PMID33335546
PMCPMC7722408

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.