Evidence map›Paper›PMID 33335471›Full record

ArticleFrontiers in neuroscience2020

Zinc Finger Transcription Factor Zbtb16 Coordinates the Response to Energy Deficit in the Mouse Hypothalamus.

Helia Cheng, Schuyler J Pablico, Jisu Lee, Ji Suk Chang, Sangho Yu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Helia Cheng'Department of Neurobiology of Nutrition and Metabolism, Louisiana State University System, Baton Rouge, LA, United States.
Schuyler J Pablico'Department of Neurobiology of Nutrition and Metabolism, Louisiana State University System, Baton Rouge, LA, United States.
Jisu LeeDepartment of Gene Regulation and Metabolism, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, United States.
Ji Suk ChangDepartment of Gene Regulation and Metabolism, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA, United States.
Sangho Yu'Department of Neurobiology of Nutrition and Metabolism, Louisiana State University System, Baton Rouge, LA, United States.
Louisiana State University System · USPennington Biomedical Research Center · US

Funding

Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leanne Maree Redman · 2005 to 2026
$26.5M
Mentoring Obesity and Diabetes Research in LouisianaP20GM103528 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI GETTYS, THOMAS W · 2012 to 2015
$8.8M
Transgenics CoreP30GM118430 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI GETTYS, THOMAS W · 2016 to 2020
$5.8M
The short isoform of PGC-1alpha in the control of brown adipose tissue thermogenesisR01DK104748 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI CHANG, JI SUK · 2015 to 2019
$1.7M
NIDDK NIH HHS P30 DK072476NIDDK NIH HHS R01 DK104748NIGMS NIH HHS P20 GM103528NIGMS NIH HHS P30 GM118430
6 · The paper itself

Abstract

The central nervous system controls feeding behavior and energy expenditure in response to various internal and external stimuli to maintain energy balance. Here we report that the newly identified transcription factor zinc finger and BTB domain containing 16 (Zbtb16) is induced by energy deficit in the paraventricular (PVH) and arcuate (ARC) nuclei of the hypothalamus via glucocorticoid (GC) signaling. In the PVH,

Indexed as

energy balanceenergy deficitenergy expenditurefood intakeglucocorticoidPLZF

Identifiers

PMID33335471
PMCPMC7736175
OpenAlexW3106817948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.