Evidence map›Paper›PMID 33335392›Full record

ReviewInternational journal of nanomedicine2020

Surface-Modified Nanocellulose for Application in Biomedical Engineering and Nanomedicine: A Review.

Silvia Tortorella, Veronica Vetri Buratti, Mirko Maturi, Letizia Sambri, Mauro Comes Franchini, Erica Locatelli

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Role of cellulose and its derivatives for 3D printing of bone tissue scaffolds.Frontiers in bioengineering and biotechnology · 2026
    Review
  3. Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  4. Review
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  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Cellulose-Based Nanomaterials Advance Biomedicine: A Review.International journal of molecular sciences · 2022
    Review
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Silvia TortorellaDepartment of Industrial Chemistry "Toso Montanari", Alma Mater Studiorum - University of Bologna, Bologna 40136, Italy.ORCID 0000-0003-4981-0795
Veronica Vetri BurattiDepartment of Industrial Chemistry "Toso Montanari", Alma Mater Studiorum - University of Bologna, Bologna 40136, Italy.ORCID 0000-0001-7102-7102
Mirko MaturiDepartment of Industrial Chemistry "Toso Montanari", Alma Mater Studiorum - University of Bologna, Bologna 40136, Italy.ORCID 0000-0003-3176-0697
Letizia SambriDepartment of Industrial Chemistry "Toso Montanari", Alma Mater Studiorum - University of Bologna, Bologna 40136, Italy.ORCID 0000-0003-1823-9872
Mauro Comes FranchiniDepartment of Industrial Chemistry "Toso Montanari", Alma Mater Studiorum - University of Bologna, Bologna 40136, Italy.ORCID 0000-0001-5765-7263
Erica LocatelliDepartment of Industrial Chemistry "Toso Montanari", Alma Mater Studiorum - University of Bologna, Bologna 40136, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presently, a plenty of concerns related to the environment are due to the overuse of petroleum-based chemicals and products; the synthesis of functional materials, starting from the natural sources, is the current trend in research. The interest for nanocellulose has recently increased in a huge range of fields, from the material science to the biomedical engineering. Nanocellulose gained this leading role because of several reasons: its natural abundance on this planet, the excellent mechanical and optical features, the good biocompatibility and the attractive capability of undergoing surface chemical modifications. Nanocellulose surface tuning techniques are adopted by the high reactivity of the hydroxyl groups available; the chemical modifications are mainly performed to introduce either charged or hydrophobic moieties that include amination, esterification, oxidation, silylation, carboxymethylation, epoxidation, sulfonation, thiol- and azido-functional capability. Despite the several already published papers regarding nanocellulose, the aim of this review involves discussing the surface chemical functional capability of nanocellulose and the subsequent applications in the main areas of nanocellulose research, such as drug delivery, biosensing/bioimaging, tissue regeneration and bioprinting, according to these modifications. The final goal of this review is to provide a novel and unusual overview on this topic that is continuously under expansion for its intrinsic sophisticated properties.

Indexed as

Biomedical EngineeringCelluloseNanomedicineNanostructuresSurface PropertiesCellulosedrug deliverynanocellusescaffoldsurface modificationtissue engineering

Identifiers

PMID33335392
PMCPMC7737557

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.