ArticleThe European respiratory journal2021
Epidemiology of pleural empyema in English hospitals and the impact of influenza.
Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06424457 (Video Assisted Thoracoscopic Surgery), which is not on this map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Video Assisted Thoracoscopic Surgery (VATS) Versus Thoracotomy in Management of Empyema in Pediatric Patients
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Pooled it
- Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial-MIST-3.American journal of respiratory and critical care medicine · 2023Trial
- A feasibility randomised trial comparing therapeutic thoracentesis to chest tube insertion for the management of pleural infection: results from the ACTion trial.BMC pulmonary medicine · 2022Trial
- The Alteplase Dose Assessment for Pleural Infection Therapy (ADAPT) Study-3: Efficacy and Safety of 1 mg Alteplase as a Starting Intrapleural Dose.Respiration; international review of thoracic diseases · 2026Article
- Cardiovascular complications after pleural infection: incidences, risk factors, and prognostic relevance.BMC cardiovascular disorders · 2026Article
- Focus on pleural empyema: etiology, epidemiology, infectiology, treatment, and impact of the COVID-19 pandemic-a single-center analysis.Journal of thoracic disease · 2026Article
- Managing pleural infections: a nationwide survey of respiratory physicians in Singapore.BMJ open respiratory research · 2026Article
- Review
- Case report of zoonotic infection ofJournal of surgical case reports · 2026Article
- Causative pathogens and clinical outcomes of pleural infection in patients without and with indwelling pleural catheters - a retrospective study from a Danish pleural clinic.European clinical respiratory journal · 2026Article
- What is new in pleural infections?Breathe (Sheffield, England) · 2026Review
- Global point prevalence study to determine the variations in aetiology, management and outcomes of pleural infection: a protocol for the international multicentre study of pleural infection (the INTERMITTENT Study).BMJ open respiratory research · 2025Article
- The role of molecular diagnostics in pleural empyema: insights from a 4-year analysis of microbial trends and antimicrobial use.Journal of medical microbiology · 2025Article
- U-shaped threshold-balanced extensive pleural lavage system for empyema: a retrospective case-control study on drainage efficiency and clinical outcomes.Journal of thoracic disease · 2025Article
- Surgical interventions for pleural infection.Breathe (Sheffield, England) · 2025Review
- Patient Preferences in empYema treatment (PAPY-study): are we investigating relevant outcomes for patients?Journal of thoracic disease · 2025Article
- A Practical Approach to Pleural Infection.Pulmonary therapy · 2025Article
- Pleural Empyema in Spain (2016-2022): A Nationwide Study on Trends in Hospitalizations, Mortality, and Impact of Comorbidities.Journal of personalized medicine · 2025Article
- Chest drainage or repeated thoracentesis for pleural infections: a clinical dilemma.Pneumonia (Nathan Qld.) · 2025Article
- Factors Associated with Complicated Parapneumonic Pleural Effusion/Empyema in Patients with Community-Acquired Pneumonia: The EMPIR Study.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
Pleural empyema represents a significant healthcare burden due to extended hospital admissions and potential requirement for surgical intervention. This study aimed to assess changes in incidence and management of pleural empyema in England over the past 10 years and the potential impact of influenza on rates.Hospital Episode Statistics data were used to identify patients admitted to English hospitals with pleural empyema between 2008 and 2018. Linear regression was used to analyse the relationship between empyema rates and influenza incidence recorded by Public Health England. The relationship between influenza and empyema was further explored using serological data from a prospective cohort study of patients presenting with pleural empyema.Between April 2008 and March 2018 there were 55 530 patients admitted with pleural empyema. There was male predominance (67%
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.