ArticleThe Lancet. Digital health2020
Adherence in children using positive airway pressure therapy: a big-data analysis.
Article in The Lancet. Digital health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06692660 (An Overview of the Use of Respiratory Support At Home in Children - Patients and Families Point of View), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Overview of the Use of Respiratory Support At Home in Children - Patients and Families Point of View
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Paediatric Long-Term Home Respiratory Support: Recommendations of the Swiss Society of Paediatric Pulmonology.Respiration; international review of thoracic diseases · 2026Guideline
- Improving Nocturnal Non-Invasive Positive Pressure Support Adherence in Children and Young Adults With Duchenne Muscular Dystrophy.Pediatric pulmonology · 2026Article
- Heated High-Flow Nasal Cannula Therapy for Pediatric Obstructive Sleep Apnea: Physiology, Clinical Evidence, and Future Directions.Children (Basel, Switzerland) · 2026Review
- Early Surgery Reduces Psychiatric and Learning Disorder Risk in Pediatric Sleep-Disordered Breathing.The Laryngoscope · 2026Article
- Dose-response relationship of sleep apnea therapy and healthcare use in patients with comorbidities.Sleep · 2026Article
- Implementation and feasibility of an interdisciplinary pediatric positive airway pressure adaptation program in a Brazilian public sleep clinic.Frontiers in sleep · 2026Article
- How adherent are children with Down syndrome and obstructive sleep apnea to positive airway pressure therapy?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Adherence to positive airway pressure therapy in patients with Down syndrome: assessing cloud-based monitoring data.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- ERS Congress 2024: highlights from the Paediatrics Assembly.ERJ open research · 2025Article
- Efficacy of atomoxetine and oxybutynin in the treatment of pediatric obstructive sleep apnea, a three case report.Frontiers in sleep · 2025Article
- The Future of Telemedicine for Obstructive Sleep Apnea Treatment: A Narrative Review.Journal of clinical medicine · 2024Review
- The lived experience of positive airway pressure therapy in patients with obstructive sleep apnea across the lifespan: a qualitative study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- The experience of children using long-term non-invasive ventilation: a qualitative study.Frontiers in sleep · 2024Article
- Oral appliance therapy and hypoglossal nerve stimulation as non-positive airway pressure treatment alternatives for obstructive sleep apnea: a narrative expert review.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Medical Treatment of Obstructive Sleep Apnea in Children.Journal of clinical medicine · 2023Review
- Behavioral and emotional characteristics of Canadian children with obesity and moderate-severe sleep-disordered breathing treated with positive airway pressure: longitudinal changes and associations with adherence.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023Article
- Adherence to Continuous Positive Airway Pressure Therapy in Pediatric Patients with Obstructive Sleep Apnea: A Meta-Analysis.Therapeutics and clinical risk management · 2023Review
- Comparison of non-invasive ventilation use and outcomes in children with Down syndrome and other children using this technology.Frontiers in sleep · 2023Article
- Recent advances in paediatric sleep disordered breathing.Breathe (Sheffield, England) · 2022Review
- A social media intervention for the families of young Black men with obstructive sleep apnoea.Health education journal · 2022Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundPositive airway pressure (PAP) has become a prominent treatment for children with sleep-disordered breathing. However, there are no large-scale studies to clarify whether PAP is well tolerated in children, and which factors are associated with better adherence to PAP therapy. In this study, we aimed to clarify adherence patterns of PAP therapy in a large paediatric population.
methodsWe did a cross-sectional big-data analysis in children from Oct 1, 2014, to Aug 1, 2018, using existing data derived from PAP devices uploaded nightly in the AirView cloud database. The AirView database is a usage tracking system available to all patients who are assigned PAP therapy, which requires consent from the patient or parent or guardian. All patients older than 4 years and younger than 18 years who used continuous or automated PAP devices were evaluated. Only patients living in the USA and enrolled with a single insurance company were included. If patients were participating in an engagement programme, programme onset must have been within 7 days of therapy onset. Our primary outcome was the proportion of patients who used PAP continuously over 90 days. The primary outcome was assessed in all patients who met the age inclusion criterion and had reliable age data available. Data on missing PAP use were imputed as zero, but data on other metrics were not imputed and excluded from analysis.
findingsWe used data recorded from Oct 1, 2014, to Aug 1, 2018. Of 40 140 children screened, 36 058 (89·8%) were US residents and 20 553 (90·1%) of them met the eligibility criteria and had accessible data (mean age 13·0 years [SD 3·7]). On the basis of 90 days of monitoring data, 12 699 (61·8%) patients continuously used PAP. Factors significantly associated with adherence included age group, residual apnoea-hypopnoea index, use and onset of patient engagement programmes, PAP pressure, and nightly median PAP mask leak, all over the 90-day study period.
interpretationTo our knowledge, our study represents the largest analysis of children using PAP therapy to date. The findings suggest that adherence to PAP therapy is lower than in previous reports from adults. However, numerous actionable factors were associated with improvements in adherence and should be used strategically in clinical decision making to improve PAP adherence in children.
fundingResMed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.