Evidence map›Paper›PMID 33334365›Full record

Observational studyReproductive health2020

Regional trends in birth weight in low- and middle-income countries 2013-2018.

Irene Marete, Osayame Ekhaguere, Carla M Bann, Sherri L Bucher, Paul Nyongesa, Archana B Patel, Patricia L Hibberd, Sarah Saleem, Robert L Goldenberg, Shivaprasad S Goudar and 11 more

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Reproductive health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01073475 (Global Network for Women's and Children's Health Research Maternal Newborn Health Registry), which is not on this map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01073475 recruitingnot on this map

Global Network for Women's and Children's Health Research Maternal Newborn Health Registry

TypeobservationalSponsorNICHD Global Network for Women's and Children's HealthRan2008 to 2030Enrolled950,000ConditionsPregnancy Outcome Trends in Low-resource Geographic AreasArmsThere is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

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  17. A prospective evaluation of tibial insertion sites for intraosseous needles to gain vascular access in Asian neonates.Journal of perinatology : official journal of the California Perinatal Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Irene MareteMoi University School of Medicine, Eldoret, Kenya. mareteirene07@yahoo.com.ORCID http://orcid.org/0000-0002-3277-5391
Osayame EkhaguereDivision of Neonatal-Perinatal Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Carla M BannRTI International, Durham, NC, USA.
Sherri L BucherDivision of Neonatal-Perinatal Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Paul NyongesaMoi University School of Medicine, Eldoret, Kenya.
Archana B PatelLata Medical Research Foundation, Nagpur, India.
Patricia L HibberdBoston University School of Public Health, Boston, MA, USA.
Sarah SaleemAga Khan University, Karachi, Pakistan.
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Columbia University School of Medicine, New York, NY, USA.
Shivaprasad S GoudarKLE Academy Higher Education and Research, J N Medical College Belagavi, Karnataka, India.
Richard J DermanThomas Jefferson University, Philadelphia, USA.
Ana L GarcesInstituto de Nutrición de Centroamérica y Panamá, Guatemala City, Guatemala.
Nancy F KrebsUniversity of Colorado School of Medicine, Denver, CO, USA.
Elwyn ChombaUniversity Teaching Hospital, Lusaka, Zambia.
Waldemar A CarloUniversity of Alabama at Birmingham, Birmingham, AL, USA.
Adrien LokangakaKinshasa School of Public Health, Kinshasa, Democratic Republic of Congo.
Melissa BausermanUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Marion Koso-ThomasEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
Janet L MooreRTI International, Durham, NC, USA.
Elizabeth M McClureRTI International, Durham, NC, USA.
Fabian EsamaiMoi University School of Medicine, Eldoret, Kenya.

Funding

The University of North Carolina-Kinshasa School of Public Health Research Partnership in the Democratic Republic of Congo; a Model for Improving Women'sand Children's Health Through ResearchUG1HD076465 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MELISSA SCHWEIKHART BAUSERMAN · 2018 to 2026
$5.6M
Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
TJU-JNMC Global Network for Women's & Children's Health Research UnitUG1HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI RICHARD J DERMAN · 2018 to 2026
$5.5M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
Columbia University/Aga Khan University Global Network Research UnitUG1HD078438 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ROBERT L GOLDENBERG · 2018 to 2026
$5.1M
Global Network for Women's and Children's Health ResearchUG1HD076461 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI BUCHER, SHERRI LYNN, SZYLD, EDGARDO GABRIEL · 2018 to 2023
$3.2M
NICHD NIH HHS UG1 HD076457NICHD NIH HHS UG1 HD076461NICHD NIH HHS UG1 HD076465NICHD NIH HHS UG1 HD076474NICHD NIH HHS UG1 HD078438NICHD NIH HHS UG1 HD078439
6 · The paper itself

Abstract

backgroundBirth weight (BW) is a strong predictor of neonatal outcomes. The purpose of this study was to compare BWs between global regions (south Asia, sub-Saharan Africa, Central America) prospectively and to determine if trends exist in BW over time using the population-based maternal and newborn registry (MNHR) of the Global Network for Women'sand Children's Health Research (Global Network).

methodsThe MNHR is a prospective observational population-based registryof six research sites participating in the Global Network (2013-2018), within five low- and middle-income countries (Kenya, Zambia, India, Pakistan, and Guatemala) in threeglobal regions (sub-Saharan Af rica, south Asia, Central America). The birth weights were obtained for all infants born during the study period. This was done either by abstracting from the infants' health facility records or from direct measurement by the registry staff for infants born at home. After controlling for demographic characteristics, mixed-effect regression models were utilized to examine regional differences in birth weights over time.

resultsThe overall BW meanswere higher for the African sites (Zambia and Kenya), 3186 g (SD 463 g) in 2013 and 3149 g (SD 449 g) in 2018, ascompared to Asian sites (Belagavi and Nagpur, India and Pakistan), 2717 g (SD450 g) in 2013 and 2713 g (SD 452 g) in 2018. The Central American site (Guatemala) had a mean BW intermediate between the African and south Asian sites, 2928 g (SD 452) in 2013, and 2874 g (SD 448) in 2018. The low birth weight (LBW) incidence was highest in the south Asian sites (India and Pakistan) and lowest in the African sites (Kenya and Zambia). The size of regional differences varied somewhat over time with slight decreases in the gap in birth weights between the African and Asian sites and slight increases in the gap between the African and Central American sites.

conclusionsOverall, BWmeans by global region did not change significantly over the 5-year study period. From 2013 to 2018, infants enrolled at the African sites demonstrated the highest BW means overall across the entire study period, particularly as compared to Asian sites. The incidence of LBW was highest in the Asian sites (India and Pakistan) compared to the African and Central American sites. Trial registration The study is registered at clinicaltrials.gov. ClinicalTrial.gov Trial Registration: NCT01073475.

Indexed as

Birth WeightDeveloping CountriesAfricaAsiaCentral AmericaChildCohort StudiesFemaleGlobal HealthHumansInfantInfant, Low Birth WeightInfant MortalityInfant, NewbornLongitudinal StudiesMaleBirth weightGlobal networkLow birth weightNeonatal mortalityNewborns

Identifiers

PMID33334365
PMCPMC7745347

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.