Evidence map›Paper›PMID 33334358›Full record

ArticleReproductive health2020

Gender variations in neonatal and early infant mortality in India and Pakistan: a secondary analysis from the Global Network Maternal Newborn Health Registry.

Zubair H Aghai, Shivaprasad S Goudar, Archana Patel, Sarah Saleem, Sangappa M Dhaded, Avinash Kavi, Parth Lalakia, Farnaz Naqvi, Patricia L Hibberd, Elizabeth M McClure and 4 more

Open access · goldAbstract read
In one paragraph

Article in Reproductive health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 71 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Zubair H AghaiThomas Jefferson University, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-5545-9706
Shivaprasad S GoudarWomen's and Children's Health Research Unit, KLE Academy of Higher Education and Research's J N Medical College, Belagavi, Karnataka, 590010, India.
Archana PatelLata Medical Research Foundation, Nagpur, India.
Sarah SaleemAga Khan University, Karachi, Pakistan.
Sangappa M DhadedWomen's and Children's Health Research Unit, KLE Academy of Higher Education and Research's J N Medical College, Belagavi, Karnataka, 590010, India.
Avinash KaviWomen's and Children's Health Research Unit, KLE Academy of Higher Education and Research's J N Medical College, Belagavi, Karnataka, 590010, India.
Parth LalakiaThomas Jefferson University, Philadelphia, PA, USA.
Farnaz NaqviAga Khan University, Karachi, Pakistan.
Patricia L HibberdSchool of Public Health, Boston University, Boston, MA, USA.
Elizabeth M McClureRTI International, Durham, NC, USA.
Tracy L NolenRTI International, Durham, NC, USA.
Pooja IyerRTI International, Durham, NC, USA.
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Columbia University School of Medicine, New York, NY, USA.
Richard J DermanThomas Jefferson University, Philadelphia, PA, USA. Richard.Derman@jefferson.edu.
KLE University · INRTI International · USThomas Jefferson University · USAga Khan University · PKBoston University · USColumbia University · USLata Medical Research Foundation · IN

Funding

Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
TJU-JNMC Global Network for Women's & Children's Health Research UnitUG1HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI RICHARD J DERMAN · 2018 to 2026
$5.5M
Columbia University/Aga Khan University Global Network Research UnitUG1HD078438 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ROBERT L GOLDENBERG · 2018 to 2026
$5.1M
NICHD NIH HHS UG1 HD076457NICHD NIH HHS UG1 HD078438NICHD NIH HHS UG1 HD078439
6 · The paper itself

Abstract

backgroundTo determine the gender differences in neonatal mortality, stillbirths, and perinatal mortality in south Asia using the Global Network data from the Maternal Newborn Health Registry.

methodsThis study is a secondary analysis of prospectively collected data from the three south Asian sites of the Global Network. The maternal and neonatal demographic, clinical characteristics, rates of stillbirths, early neonatal mortality (1-7 days), late neonatal mortality (8-28 days), mortality between 29-42 days and the number of infants hospitalized after birth were compared between the male and female infants.

resultsBetween 2010 and 2018, 297,509 births [154,790 males (52.03%) and 142,719 females (47.97%)] from two Indian sites and one Pakistani site were included in the analysis [288,859 live births (97.1%) and 8,648 stillbirths (2.9%)]. The neonatal mortality rate was significantly higher in male infants (33.2/1,000 live births) compared to their female counterparts (27.4/1,000, p < 0.001). The rates of stillbirths (31.0 vs. 26.9/1000 births) and early neonatal mortality (27.1 vs 21.6/1000 live births) were also higher in males. However, there were no significant differences in late neonatal mortality (6.3 vs. 5.9/1000 live births) and mortality between 29-42 days (2.1 vs. 1.9/1000 live births) between the two groups. More male infants were hospitalized within 42 days after birth (1.8/1000 vs. 1.3/1000 live births, p < 0.001) than females.

conclusionThe risks of stillbirths, and early neonatal mortality were higher among male infants than their female counterparts. However, there was no gender difference in mortality after 7 days of age. Our results highlight the importance of stratifying neonatal mortality into early and late neonatal period to better understand the impact of gender on neonatal mortality. The information from this study will help in developing strategies and identifying measures that can reduce differences in sex-specific mortality.

Indexed as

Infant MortalitySex FactorsAdultFemaleHumansIndiaInfantInfant HealthInfant, NewbornMalePakistanPregnancyRegistriesStillbirthEarly neonatal mortalityGlobal networkLate neonatal mortalityLow-middle income countriesSex variation in mortalityStillbirth

Identifiers

PMID33334358
PMCPMC7745348
OpenAlexW3112474763

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.