Evidence map›Paper›PMID 33334337›Full record

ArticleReproductive health2020

Institutional deliveries and stillbirth and neonatal mortality in the Global Network's Maternal and Newborn Health Registry.

Shivaprasad S Goudar, Norman Goco, Manjunath S Somannavar, Avinash Kavi, Sunil S Vernekar, Antoinette Tshefu, Elwyn Chomba, Ana L Garces, Sarah Saleem, Farnaz Naqvi and 14 more

Registry-linked trialAbstract read
In one paragraph

Article in Reproductive health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01073475 (Global Network for Women's and Children's Health Research Maternal Newborn Health Registry), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01073475 recruitingnot on this map

Global Network for Women's and Children's Health Research Maternal Newborn Health Registry

TypeobservationalSponsorNICHD Global Network for Women's and Children's HealthRan2008 to 2030Enrolled950,000ConditionsPregnancy Outcome Trends in Low-resource Geographic AreasArmsThere is no intervention associated with the parent MNHR study. For the MNHR COVID sub-study, participants will be asked to provide a blood specimen at or near delivery.
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Perinatal mortality in eastern Africa: A systematic review and meta-analysis.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  11. Institutional Delivery in the Philippines: Does a Minimum of 8 Antenatal Care Visits Matter?Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Shivaprasad S GoudarKLE Academy of Higher Education and Research Jawaharlal Nehru Medical College, Belagavi, Karnataka, India. sgoudar@jnmc.edu.
Norman GocoRTI International, Durham, NC, USA.
Manjunath S SomannavarKLE Academy of Higher Education and Research Jawaharlal Nehru Medical College, Belagavi, Karnataka, India.
Avinash KaviKLE Academy of Higher Education and Research Jawaharlal Nehru Medical College, Belagavi, Karnataka, India.
Sunil S VernekarKLE Academy of Higher Education and Research Jawaharlal Nehru Medical College, Belagavi, Karnataka, India.
Antoinette TshefuKinshasa School of Public Health, Kinshasa, Democratic Republic of Congo.
Elwyn ChombaUniversity Teaching Hospital, Lusaka, Zambia.
Ana L GarcesInstituto de Nutrición de Centroamérica y Panamá, Guatemala City, Guatemala.
Sarah SaleemAga Khan University, Karachi, Pakistan.
Farnaz NaqviAga Khan University, Karachi, Pakistan.
Archana PatelLata Medical Research Foundation, Nagpur, India.
Fabian EsamaiMoi University School of Medicine, Eldoret, Kenya.
Carl L BoseUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Waldemar A CarloUniversity of Alabama at Birmingham, Birmingham, AL, USA.
Nancy F KrebsUniversity of Colorado School of Medicine, Denver, CO, USA.
Patricia L HibberdBoston University School of Public Health, Boston, MA, USA.
Edward A LiechtyIndiana School of Medicine, University of Indiana, Indianapolis, IN, USA.
Marion Koso-ThomasEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.
Tracy L NolenRTI International, Durham, NC, USA.
Janet MooreRTI International, Durham, NC, USA.
Pooja IyerRTI International, Durham, NC, USA.
Elizabeth M McClureRTI International, Durham, NC, USA.ORCID http://orcid.org/0000-0001-8659-5444
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Columbia University School of Medicine, New York, NY, USA.
Richard J DermanThomas Jefferson University, Philadelphia, PA, USA.

Funding

Global Network for Women's and Children's Health Research Data Coordinating CenterU24HD092094 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI Elizabeth M McClure · 2017 to 2026
$17.8M
The University of North Carolina-Kinshasa School of Public Health Research Partnership in the Democratic Republic of Congo; a Model for Improving Women'sand Children's Health Through ResearchUG1HD076465 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MELISSA SCHWEIKHART BAUSERMAN · 2018 to 2026
$5.6M
Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
TJU-JNMC Global Network for Women's & Children's Health Research UnitUG1HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI RICHARD J DERMAN · 2018 to 2026
$5.5M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
Columbia University/Aga Khan University Global Network Research UnitUG1HD078438 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ROBERT L GOLDENBERG · 2018 to 2026
$5.1M
Global Network for Women's and Children's Health ResearchUG1HD076461 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI BUCHER, SHERRI LYNN, SZYLD, EDGARDO GABRIEL · 2018 to 2023
$3.2M
Eunice Kennedy Shriver National Institute of Child Health and Human Development U24HD92094NICHD NIH HHS U24 HD092094NICHD NIH HHS UG1 HD076457NICHD NIH HHS UG1 HD076461NICHD NIH HHS UG1 HD076465NICHD NIH HHS UG1 HD076474NICHD NIH HHS UG1 HD078438NICHD NIH HHS UG1 HD078439
6 · The paper itself

Abstract

backgroundFew studies have shown how the move toward institutional delivery in low and middle-income countries (LMIC) impacts stillbirth and newborn mortality.

objectivesThe study evaluated trends in institutional delivery in research sites in Belagavi and Nagpur India, Guatemala, Kenya, Pakistan, and Zambia from 2010 to 2018 and compared them to changes in the rates of neonatal mortality and stillbirth.

methodsWe analyzed data from a nine-year interval captured in the Global Network (GN) Maternal Newborn Health Registry (MNHR). Mortality rates were estimated from generalized estimating equations controlling for within-cluster correlation. Cluster-level analyses were performed to assess the association between institutional delivery and mortality rates.

resultsFrom 2010 to 2018, a total of 413,377 deliveries in 80 clusters across 6 sites in 5 countries were included in these analyses. An increase in the proportion of institutional deliveries occurred in all sites, with a range in 2018 from 57.7 to 99.8%. In 2010, the stillbirth rates ranged from 19.3 per 1000 births in the Kenyan site to 46.2 per 1000 births in the Pakistani site and by 2018, ranged from 9.7 per 1000 births in the Belagavi, India site to 40.8 per 1000 births in the Pakistani site. The 2010 neonatal mortality rates ranged from 19.0 per 1000 live births in the Kenyan site to 51.3 per 1000 live births in the Pakistani site with the 2018 neonatal mortality rates ranging from 9.2 per 1000 live births in the Zambian site to 50.2 per 1000 live births in the Pakistani site. In multivariate modeling, in some but not all sites, the reductions in stillbirth and neonatal death were significantly associated with an increase in the institutional deliveries.

conclusionsThere was an increase in institutional delivery rates in all sites and a reduction in stillbirth and neonatal mortality rates in some of the GN sites over the past decade. The relationship between institutional delivery and a decrease in mortality was significant in some but not all sites. However, the stillbirth and neonatal mortality rates remain at high levels. Understanding the relationship between institutional delivery and stillbirth and neonatal deaths in resource-limited environments will enable development of targeted interventions for reducing the mortality burden.

trial registrationThe study is registered at clinicaltrials.gov . ClinicalTrial.gov Trial Registration: NCT01073475 .

Indexed as

Infant MortalityAdultDelivery, ObstetricFemaleHealth FacilitiesHumansInfantInfant HealthInfant, NewbornMaleMaternal AgePregnancyRegistriesStillbirthFacility birthsGlobal networkInstitutional deliveriesNeonatal mortalityStillbirths

Identifiers

PMID33334337
PMCPMC7745350

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.