Evidence map›Paper›PMID 33334266›Full record

ArticleInternational journal of STD & AIDS2021

HIV-related enacted stigma and increase frequency of depressive symptoms among Thai and Cambodian adolescents and young adults with perinatal HIV.

Linda Aurpibul, Jiratchaya Sophonphan, Kathleen Malee, Stephen J Kerr, Ly Penh Sun, Pradthana Ounchanum, Pope Kosalaraksa, Chaiwat Ngampiyaskul, Suparat Kanjanavanit, Kea Chettra and 7 more

Open access · greenAbstract read
In one paragraph

Article in International journal of STD & AIDS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 12 institutions in 4 countries.

Linda AurpibulResearch Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand.ORCID 0000-0003-0246-8187
Jiratchaya SophonphanThe HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), The Thai Red Cross AIDS Research Center, Bangkok, Thailand.
Kathleen MaleeDepartment of Psychiatry and Behavioral Science, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Stephen J KerrThe HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), The Thai Red Cross AIDS Research Center, Bangkok, Thailand.
Ly Penh SunNational Center for HIV/AIDS Dermatology and STDs, Phnom Penh, Cambodia.
Pradthana OunchanumChiangrai Prachanukroh Hospital, Chiang Rai, Thailand.
Pope KosalaraksaDepartment of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Chaiwat NgampiyaskulPrapokklao Hospital, Chanthaburi, Thailand.
Suparat KanjanavanitNakornping Hospital, Chiang Mai, Thailand.
Kea ChettraNational Center for HIV/AIDS Dermatology and STDs, Phnom Penh, Cambodia.
Tulathip SuwanlerkThe HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), The Thai Red Cross AIDS Research Center, Bangkok, Thailand.
Claude A MellinsHIV Center for Clinical and Behavioral Studies, Department of Psychiatry, New York State Psychiatric Institute, and Columbia University, New York, NY, USA.
Robert PaulMissouri Institute of Mental Health, University of Missouri-St. Louis, MO, USA.
Reuben N RobbinsHIV Center for Clinical and Behavioral Studies, Department of Psychiatry, New York State Psychiatric Institute, and Columbia University, New York, NY, USA.
Jintanat AnanworanichThe Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Thanyawee PuthanakitThe HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), The Thai Red Cross AIDS Research Center, Bangkok, Thailand.
PREDICT Resilience study
Chulalongkorn University · THHIV Netherlands Australia Thailand Research Collaboration · THNational Center for HIV/AIDS, Dermatology and STD · KHNew York Psychoanalytic Society and Institute · USChiang Mai University · THChiangRai Prachanukroh Hospital · THHenry M. Jackson Foundation · USKhon Kaen University · THNakornping Hospital · THNorthwestern University · USPrapokklao Hospital · THUniversity of Missouri–St. Louis · US

Funding

Treatment of HIV/Tuberculosis Co-DiseaseU19AI053741 · NIAID · HIV-NAT, THE THAI RED CROSS AIDS RCH CTR · PI RUXRUNGTHAM, KIAT · 2004 to 2010
$6.3M
Neurodevelopment and Imaging among HIV-infected Children from the PREDICT studyR01MH089722 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VALCOUR, VICTOR · 2010 to 2014
$3.1M
Determinants of Resilience in Youth with HIV infection and Youth affected by HIVR01MH102151 · NIMH · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI ROBB, MERLIN L · 2014 to 2018
$2.3M
NIAID NIH HHS U19 AI053741NIMH NIH HHS R01 MH089722NIMH NIH HHS R01 MH102151
6 · The paper itself

Abstract

HIV-related enacted stigma and social problems may increase risk for depression and/or behavioral problems among adolescents and young adults with perinatal HIV(AYA-PHIV), yet few studies have explored stigma in AYA-PHIV residing in low-to-middle income regions, including Southeast Asia. We assessed HIV-related enacted stigma and social problems in AYA-PHIV who participated in the RESILIENCE study (clinicaltrials.gov identification: U19AI53741) in Thailand and Cambodia using specific questions during structured in-person interviews. Depression was measured by the Child Depression Inventory for children <15 years, or the Center for Epidemiologic Studies Depression Scales for youth ≥15 years); behavioral problems were measured by the Child Behavior Checklist (CBCL-caregiver report). Among 195 AYA-PHIV (median age 16.9 years), 25.6% reported a lifetime experience of enacted stigma, while 10.8% experienced social problems due to HIV infection. The frequency of depressive symptoms was nearly two-fold higher among AYA-PHIV with compared to those without HIV-related enacted stigma (34.7% vs. 16.0%, p = 0.005). Caregiver-reported behavioral problems were detected in 14.6% of all AYA-PHIV, with no differences between those with and without HIV-related enacted stigma. Low household income and caregiver mental health problems were independent risk factors for depressive symptoms; HIV-related enacted stigma was also associated with increased risk, warranting targeted services to support AYA-PHIV.

Indexed as

Social StigmaAdolescentAffective SymptomsAnti-HIV AgentsAsian PeopleCambodiaCaregiversChildCross-Sectional StudiesDepressionDiscrimination, PsychologicalFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalMental HealthAnti-HIV AgentsAdolescentbehavioral problemdepressive symptomsenacted stigmaperinatal HIV infectionyoung adults

Identifiers

PMID33334266
PMCPMC10849772
OpenAlexW3114738804

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.