Evidence map›Paper›PMID 33334213›Full record

ArticleTissue engineering. Part C, Methods2021

Protein-Functionalized Poly(ethylene glycol) Hydrogels as Scaffolds for Monolayer Organoid Culture.

Reid L Wilson, Ganesh Swaminathan, Khalil Ettayebi, Carolyn Bomidi, Xi-Lei Zeng, Sarah E Blutt, Mary K Estes, K Jane Grande-Allen

Open access · greenAbstract read
In one paragraph

Article in Tissue engineering. Part C, Methods, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Organoids for disease modeling and treatment: state-of-the-art.Experimental hematology & oncology · 2026
    Review
  4. 3DACS biomaterials science & engineering · 2026
    Review
  5. Review
  6. Review
  7. Organoid scaffold materials: research and application.Frontiers in bioengineering and biotechnology · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Skeletal organoids.Biomaterials translational · 2024
    Review
  12. Addressing Key Questions in Organoid Models: Who, Where, How, and Why?International journal of molecular sciences · 2023
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Reid L WilsonDepartment of Bioengineering, Rice University, Houston, Texas, USA.
Ganesh SwaminathanDepartment of Bioengineering, Rice University, Houston, Texas, USA.
Khalil EttayebiMolecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Carolyn BomidiMolecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Xi-Lei ZengMolecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Sarah E BluttMolecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Mary K EstesMolecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
K Jane Grande-AllenDepartment of Bioengineering, Rice University, Houston, Texas, USA.
Baylor College of Medicine · USRice University · US

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
Novel Platforms for Human Intestinal Enteroids: Matrix, Mechanics, and TopographyU19AI116497 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI GRANDE-ALLEN, KATHRYN JANE · 2015 to 2025
$13.2M
Novel biomaterial and biomechanical platforms for modeling the small intestineF30DK108541 · NIDDK · RICE UNIVERSITY · PI WILSON, REID LAURENCE · 2016 to 2019
$164k
NIAID NIH HHS U19 AI116497NIDDK NIH HHS F30 DK108541NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

Stem cell-derived, organotypic

Indexed as

HydrogelsOrganoidsBiocompatible MaterialsCell Culture TechniquesHumansPolyethylene GlycolsBiocompatible MaterialsHydrogelsPolyethylene Glycolscell-adhesive peptidesnorovirusorganoidprotein functionalization

Identifiers

PMID33334213
PMCPMC7826425
OpenAlexW3112057393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.