ArticleThe International journal of social psychiatry2022
Social relationship quality, depression and inflammation: A cross-cultural longitudinal study in the United States and Tokyo, Japan.
Article in The International journal of social psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Estimating survival in data-driven phenotypes of mental health symptoms and peripheral biomarkers: A prospective study.Brain, behavior, & immunity - health · 2024Article
- Causal relationships involving brain imaging-derived phenotypes based on UKB imaging cohort: a review of Mendelian randomization studies.Frontiers in neuroscience · 2024Review
- Examining the Relationships between the Incidence of Infectious Diseases and Mood Disorders: An Analysis of Data from the Global Burden of Disease Studies, 1990-2019.Diseases (Basel, Switzerland) · 2023Article
- Dissecting the causal association between social or physical inactivity and depression: a bidirectional two-sample Mendelian Randomization study.Translational psychiatry · 2023Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundDepression is an illness with biological, psychological, and social underpinnings, which may include the interplay of inflammation, psychological traits, stress, social relationships, and cultural background.
aimsThis work examines the prospective associations between social relationship quality and depressive symptoms, and between social relationship quality and inflammatory outcomes in two distinct cultures.
methodsData were obtained from two longitudinal, prospective cohort studies: Midlife in the United States (MIDUS), and Midlife Development in Japan (MIDJA) between 2004 and 2010. One thousand three hundred and twenty-seven community-based adults were included in analyses, 1,054 from the United States and 273 from Tokyo, Japan. Depressive symptoms (measured by the CES-D Depression Scale) and inflammation (measured by blood sample concentrations of the inflammatory biomarkers interleukin-6 and C-reactive protein) were the outcomes. Social relationship quality was the predictor. Culture, trait independence and interdependence, and psychosocial stressors were examined as moderators of the link between social relationship quality and depressive symptoms.
resultsHigher social relationship quality was associated with lower depressive symptoms in the United States (β = -6.15,
conclusionImproving the perceived quality of social relationships appears to be a stronger target for depression interventions in the United States than in Tokyo, Japan.
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