Evidence map›Paper›PMID 33333865›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Novel Isoniazid-Carborane Hybrids Active in Vitro Against

Daria Różycka, Małgorzata Korycka-Machała, Anna Żaczek, Jarosław Dziadek, Dorota Gurda, Marta Orlicka-Płocka, Eliza Wyszko, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Agnieszka B Olejniczak

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Reduced fitness and enhanced immunogenicity ofCurrent research in microbial sciences · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Daria RóżyckaInstitute of Medical Biology, Polish Academy of Sciences, 106 Lodowa St., 93-232 Lodz, Poland.
Małgorzata Korycka-MachałaInstitute of Medical Biology, Polish Academy of Sciences, 106 Lodowa St., 93-232 Lodz, Poland.
Anna ŻaczekInstitute of Medical Sciences, Medical College, University of Rzeszow, 2A Kopisto Avenue, 35-959 Rzeszow, Poland.
Jarosław DziadekInstitute of Medical Biology, Polish Academy of Sciences, 106 Lodowa St., 93-232 Lodz, Poland.ORCID 0000-0003-1427-884X
Dorota GurdaInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 12/14Z. Noskowskiego St., 61-704 Poznan, Poland.
Marta Orlicka-PłockaInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 12/14Z. Noskowskiego St., 61-704 Poznan, Poland.
Eliza WyszkoInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 12/14Z. Noskowskiego St., 61-704 Poznan, Poland.
Katarzyna Biniek-AntosiakInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 12/14Z. Noskowskiego St., 61-704 Poznan, Poland.
Wojciech RypniewskiInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 12/14Z. Noskowskiego St., 61-704 Poznan, Poland.ORCID 0000-0002-6097-5518
Agnieszka B OlejniczakInstitute of Medical Biology, Polish Academy of Sciences, 106 Lodowa St., 93-232 Lodz, Poland.ORCID 0000-0003-4628-9017
Institute of Bioorganic Chemistry, Polish Academy of Sciences · PLInstitute for Medical Biology · PLUniversity of Rzeszów · PL

Funding

Institute of Medical Biology Polish Academy of Sciences T-76The National Science Centre 2014/14/E/ST5/00577
6 · The paper itself

Abstract

Tuberculosis (TB) is a severe infectious disease with high mortality and morbidity. The emergence of drug-resistant TB has increased the challenge to eliminate this disease. Isoniazid (INH) remains the key and effective component in the therapeutic regimen recommended by World Health Organization (WHO). A series of isoniazid-carborane derivatives containing 1,2-dicarba-

Indexed as

antitubercular activityboron clustercarboraneisoniazidMycobacterium tuberculosis

Identifiers

PMID33333865
PMCPMC7765321
OpenAlexW3112974045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.