Evidence map›Paper›PMID 33333853›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Introduction of a Simplified Psoriatic Arthritis Magnetic Resonance Imaging Score (sPsAMRIS): A Potential Tool for Treatment Monitoring in Peripheral Psoriatic Arthritis.

Daniel B Abrar, Christoph Schleich, Ralph Brinks, Christine Goertz, Miriam Frenken, Matthias Schneider, Sven Nebelung, Philipp Sewerin

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel B AbrarDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, D-40225 Dusseldorf, Germany.ORCID 0000-0002-8116-4431
Christoph SchleichDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, D-40225 Dusseldorf, Germany.
Ralph BrinksDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine University Düsseldorf, D-40225 Dusseldorf, Germany.
Christine GoertzDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine University Düsseldorf, D-40225 Dusseldorf, Germany.
Miriam FrenkenDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, D-40225 Dusseldorf, Germany.
Matthias SchneiderDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine University Düsseldorf, D-40225 Dusseldorf, Germany.
Sven NebelungDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Dusseldorf, D-40225 Dusseldorf, Germany.ORCID 0000-0002-5267-9962
Philipp SewerinDepartment and Hiller-Research-Unit for Rheumatology, UKD, Heinrich-Heine University Düsseldorf, D-40225 Dusseldorf, Germany.ORCID 0000-0001-8465-6207

Funding

Bundesministerium für Bildung und Forschung 01EC1009Deutsche Forschungsgemeinschaft NE 2136/3-1Medizinische Fakultät, Heinrich-Heine-Universität Düsseldorf nonePfizer Health Research Foundation Pfizer GIP Inflammation Germany Research Initiative
6 · The paper itself

Abstract

backgroundTo evaluate whether a simplified (s) version of the psoriatic arthritis magnetic resonance imaging score (PsAMRIS), sPsAMRIS, is a potential tool for therapy monitoring in psoriatic arthritis (PsA).

methodsSeventeen patients with active psoriatic arthritis (PsA) underwent magnetic resonance imaging (MRI) at 3 T of the clinically dominant hand at baseline and after 6 months. Scoring was performed by two musculoskeletal radiologists in terms of the PsAMRIS and sPsAMRIS, which is a simplified version with reduced item numbers based on prior evaluation of responsiveness to change by standardized response means (SRMs). Both scores were compared by calculation of overall and each sub-score's SRMs and relative efficacy (RE) after bootstrapping.

resultsPsAMRIS sub-scores of MCP joints 3 and 4, and proximal interphalangeal (PIP) joint 4 had the highest SRM (-0.07 each), indicating highest responsiveness to change, and were, therefore, included in sPsAMRIS. Compared to PsAMRIS, sPsAMRIS was characterized by higher SRMs (sPsAMRIS: -0.13 vs. PsAMRIS: -0.02) and higher RE (29.46). sPsAMRIS and PsAMRIS were highly correlated at baseline (r = 0.75,

conclusionDue to its similar responsiveness to change compared to standard PsAMRIS, and time efficiency, sPsAMRIS might be a potential diagnostic tool to quantitatively assess and monitor therapy in PsA.

Indexed as

magnetic resonance imagingOMERACTPsAMRISpsoriatic arthritis

Identifiers

PMID33333853
PMCPMC7765290

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