ArticleJournal of clinical medicine2020
Prevalence of Neuropathic Pain and Related Characteristics in Hidradenitis Suppurativa: A Cross-Sectional Study.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Neuropathic Pain Management Using Novel Biologics in Moderate-to-Severe Hidradenitis Suppurativa.Current pain and headache reports · 2026Review
- A Neuroendocrine-Immune Model of Hidradenitis Suppurativa: Mechanistic Insights into Pain, Pruritus, and Hormonal Triggers.Journal of clinical medicine · 2026Review
- Nerves and nodules: Mononeuritis multiplex as a reversible complication of severe Hidradenitis Suppurativa.JAAD case reports · 2026Article
- Patient involvement in treatment decisions is associated with increased therapy satisfaction in Hidradenitis suppurativa.Frontiers in medicine · 2025Article
- Burden of Hidradenitis Suppurativa: A Systematic Literature Review of Patient Reported Outcomes.Dermatology and therapy · 2024Review
- Pain experiences among those living with hidradenitis suppurativa: a qualitative study.The British journal of dermatology · 2023Article
- Pain measurement in painful skin conditions and rheumatoid arthritis randomized controlled trials: a scoping review to inform pain measurement in hidradenitis suppurativa.The British journal of dermatology · 2022Article
- New treatments and new assessment instruments for Hidradenitis suppurativa.Experimental dermatology · 2022Review
- Dermatological Conditions Inducing Acute and Chronic Pain.Acta dermato-venereologica · 2022Review
- [Epidemiology, patient quality of life, and treatment costs of hidradenitis suppurativa/acne inversa].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021Review
- Can chronic spontaneous urticarial produce symptoms of neuropathic pain?Anais brasileiros de dermatologiaArticle
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPain is a core symptom of hidradenitis suppurativa (HS) and is of complex, multifactorial origin. HS patients frequently report typical neuropathic pain qualities, but its prevalence has been poorly described.
methodsIn this cross-sectional study, we examine the prevalence of neuropathic pain (NP) component and related pain-characteristics of a hospital-based cohort of patients with symptomatic HS. We administered the pain-DETECT tool (PDQ), a validated screening tool for NP, collecting clinical and patient-reported data on pain, pruritus and pain-management. We obtained 110 complete datasets from symptomatic HS patients (49.1% females; Hurley I (27.3%])-II (45.5%)-III (27.3%)). According to the PDQ tool, 30% of patients were classified with a high probability (>90%) of neuropathic pain (LNP). LNP status was significantly associated with increased pain severity, disease activity, pruritus intensity and use of pain medication. Regression analysis showed a significant impact of the PDQ score on patient-reported outcomes, including pain severity and the dimensions of activity and affective pain interference. HS patients may present a mixed chronic pain phenotype with a neuropathic component, thus requiring additional pain-assessments. A multi-modal approach to pain management, in combination with disease-specific treatment, should be implemented in future interventional studies.
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