ArticleChildren (Basel, Switzerland)2020
Publication Trends of Pediatric and Adult Randomized Controlled Trials in General Medical Journals, 2005-2018: A Citation Analysis.
Article in Children (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical Trials in Central Venous Access Devices: An Evidence and Gap Map.Journal of advanced nursing · 2026Pooled it
- The Trial Bank initiative to promote trustworthy living evidence for medication safety (PROMISE) of children: design and pilot validation.BMC medicine · 2026Article
- Prioritization of Randomized Clinical Trial Questions for Children Hospitalized With Common Conditions: A Consensus Statement.JAMA network open · 2024Article
- Clinical Trials for Special Populations: Children, Older Adults, and Rare Diseases.Mayo Clinic proceedings · 2024Review
- Online randomised trials with children: A scoping review.PloS one · 2023Article
- New and Old Challenges in Pediatric Health Policies.Children (Basel, Switzerland) · 2022Article
- Patient, Caregiver, and Clinician Participation in Prioritization of Research Questions in Pediatric Hospital Medicine.JAMA network open · 2022Article
- Prevalence, Cost, and Variation in Cost of Pediatric Hospitalizations in Ontario, Canada.JAMA network open · 2022Article
- Online randomised trials with children: A scoping review protocol.HRB open research · 2022Article
- Managing paediatric gastroenteritis in primary care: is there a role for ondansetron?The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Article
- Identifying Conditions With High Prevalence, Cost, and Variation in Cost in US Children's Hospitals.JAMA network open · 2021Article
- [Opinions on clinical research and scientific paper publication].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Policy has been developed to promote the conduct of high-quality pediatric randomized controlled trials (RCTs). Whether these strategies have influenced publication trends in high-impact journals is unknown. We aim to evaluate characteristics, citation patterns, and publication trends of pediatric RCTs published in general medical journals (GMJs) compared with adult RCTs over a 13-year period. Studies were identified using Medline, and impact metrics were collected from Web of Science and Scopus. All RCTs published from 2005-2018 in 7 GMJs with the highest impact factors were identified for analysis. A random sample of matched pediatric and adult RCTs were assessed for publication characteristics, academic and non-academic citation. Citations were counted from publication until June 2019. Among 4146 RCTs, 2794 (67.3%) enrolled adults, 591 (14.2%) enrolled children, and 761 RCTs (18.3%) enrolled adult and pediatric patients. Adult RCTs published in GMJs grew by 5.1 publications per year (95% CI: 3.3-6.9), while the number of pediatric RCTs did not show significant change (-0.4 RCTs/year, 95% CI: -1.4-0.6). Adult RCTs were cited more than pediatric RCTs (median(IQR): 29.9 (68.5-462.8) citations/year vs. 13.2 (6.8-24.9) citations/year;
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.