Evidence map›Paper›PMID 33333515›Full record

ArticleAmerican journal of nephrology2020

Availability and Affordability of Kidney Health Laboratory Tests around the Globe.

Sri Lekha Tummalapalli, Michael G Shlipak, Sandrine Damster, Vivekanand Jha, Charu Malik, Adeera Levin, David W Johnson, Aminu K Bello

Open access · bronzeAbstract read
In one paragraph

Article in American journal of nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

  1. Are your kidneys okay? Detect early to protect kidney health.Kidney research and clinical practice · 2026
    Article
  2. Article
  3. Article
  4. Are your kidneys ok? Detect early to protect kidney health.Clinical and experimental nephrology · 2025
    Article
  5. Are Your Kidneys Ok? Detect Early to Protect Kidney Health.American journal of hypertension · 2025
    Review
  6. Article
  7. Article
  8. Are Your Kidneys Ok? Detect Early to Protect Kidney Health.Canadian journal of kidney health and disease · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. What should European nephrology do with the new CKD-EPI equation?Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Sri Lekha TummalapalliKidney Health Research Collaborative, Department of Medicine, San Francisco Veterans Affairs Medical Center and University of California, San Francisco, California, USA, lct4001@med.cornell.edu.
Michael G ShlipakKidney Health Research Collaborative, Department of Medicine, San Francisco Veterans Affairs Medical Center and University of California, San Francisco, California, USA.
Sandrine DamsterInternational Society of Nephrology, Brussels, Belgium.
Vivekanand JhaGeorge Institute for Global Health, UNSW, New Delhi, India.
Charu MalikInternational Society of Nephrology, Brussels, Belgium.
Adeera LevinDivision of Nephrology, University of British Columbia, Vancouver, British Columbia, Canada.
David W JohnsonCentre for Kidney Disease Research, University of Queensland, Brisbane, Queensland, Australia.
Aminu K BelloDivision of Nephrology & Immunology, University of Alberta, Edmonton, Alberta, Canada.
Cornell University · USManipal Academy of Higher Education · INPrincess Alexandra Hospital · AUUniversity of Alberta · CAUniversity of British Columbia · CAUniversity of California, San Francisco · US

Funding

Screening Strategies for Chronic Kidney Disease in US PopulationsF32DK122627 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI TUMMALAPALLI, SRI LEKHA · 2019 to 2021
$159k
NIDDK NIH HHS F32 DK122627
6 · The paper itself

Abstract

backgroundKidney disease is a major global public health problem, and laboratory testing of kidney health measures is essential for diagnosis and monitoring. The availability and affordability of kidney health laboratory tests across countries has not been systematically described.

methodsThe International Society of Nephrology (ISN), in partnership with leaders of a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference, surveyed a representative subset of ISN-Global Kidney Health Atlas (ISN-GKHA) respondents from April to June 2020. We assessed the association between country gross national income (GNI) per capita and laboratory testing availability and affordability.

resultsOf 33 regional expert nephrologists invited, 24 (73%) responded, representing all 10 ISN regions around the world. Availability of kidney health laboratory tests was as follows: serum Cr (100%), serum cystatin C (67%), urine albumin (96%), urine Cr (100%), and dipstick urinalysis (100%). Median (IQR) reimbursement values in international dollars were as follows: serum Cr Int$ 6.61 (3.42-8.84), serum cystatin C Int$ 31.51 (17.36-46.25), urine albumin Int$ 10.22 (5.90-15.42), urine Cr Int$ 7.50 (1.66-8.84), and dipstick urinalysis Int$ 6.26 (2.56-8.40). Reimbursement values did not differ significantly by World Bank income group or by GNI per capita.

conclusionThere was widespread availability of kidney health laboratory tests and substantial variation in reimbursement values. To achieve meaningful progress across nations in mitigating the growth of kidney disease, access to affordable diagnostic technology is essential. Our results are highly relevant to policymakers and researchers as countries increasingly consider national strategies for kidney disease detection and management.

Indexed as

Costs and Cost AnalysisHealth Services AccessibilityHumansInternationalityKidney Function TestsAccessAffordabilityChronic kidney diseaseDiagnosticsGlobal healthLaboratory testing

Identifiers

PMID33333515
PMCPMC8482418
OpenAlexW3112862730

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.